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Purified anti-DDX3X Antibody
产品名称：
Purified anti-DDX3X Antibody
产品类别：
抗体
产品编号：
658602
产品应用：
658602
[价格]
规格 价格 库存
100µg ￥ 4858 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human DDX3X recombinant protein (1-226aa)
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC, IP - Verified
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per ml. For immunocytochemistry, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. For immunoprecipitation, the suggested use of this reagent is 5.0 - 20 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Gordon DE, et al. 2020. Molecular Cell. 78(2):197-209. PubMed
RRID
AB_2562957 (BioLegend Cat. No. 658602)

Antigen Details

Structure
662 amino acids, predicted molecular weight of 73 kD. Contains a ATP-dependent helicase domain.
Distribution

Nucleus, Cytoplasm

Function
DDX3X is an ATP-dependent RNA helicase, involving in mRNA transcription, maturation, export, and translation.
Interaction
Interacts with DDX5, DDX58, IKK??, TBK1, XPO1, TDRD3, PABPC1, NXF1, EIF3C, MAVS, and NCAPH.
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Immunology, Innate Immunity, Protein Synthesis
Antigen References

1. Lai MC, et al. 2013. PLoS One. 8:e68665.
2. Bol GM, et al. 2013. PLoS One. 8:e63548.
3. Soto-Rifo R, et al. 2012. EMBO J. 31:3745.
4. Gu L, et al. 2013. Mol. Cell Biol. 33:2004.
5. Wang H, et al. 2009. J. Virol. 83:5815.
6. Lee CS, et al. 2008. Nucleic Acids Res. 36:4708.

Gene ID
1654 View all products for this Gene ID
UniProt
View information about DDX3X on UniProt.org

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