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首页 > 抗体蛋白 > 抗体
Purified anti-CDKN2A (p16) Antibody
产品名称：
Purified anti-CDKN2A (p16) Antibody
产品类别：
抗体
产品编号：
675602
产品应用：
675602
[价格]
规格 价格 库存
100µg ￥ 4354 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full length human CDKN2A recombinant protein expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB -?Quality tested
ICC, KO/KD-WB?- Verified
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Puca AA, et al. 2022. Cells. 11:. PubMed
  2. Diaz-Flores E, et al. 2019. Cancer Res. 79:2339. PubMed
RRID
AB_2565605 (BioLegend Cat. No. 675602)

Antigen Details

Structure
156 amino acids with a predicted molecular weight of 16.5 kD. It contains 4 ANK repeats that are responsible for protein-protein interaction.
Distribution

Cytoplasm and nucleus.

Function
CDKN2A is an inhibitor of the cyclin dependent kinases CDK4 and CDK6, which plays an imporant role in controlling cell cycle progression from the G1 phase to S phase.
Interaction
CDKN2A forms a heterodimer with CDK4 or CDK6.
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication
Antigen References

1. Di Cello F, et al. 2013. Leuk. Lymphoma. 54:1762.
2. Shima K, et al. 2011. Int. J. Cancer 128:1080.
3. Baker DJ, et al. 2008. Cell Cycle 7:2795.
4. Jones R, et al. 2007. Cancer Res. 67:9134.
5. Ladanyi M. 2005. Lung Cancer 49:S95.
6. Foulkes WD, et al. 1997. Mol. Med. 3:5.

Gene ID
1029 View all products for this Gene ID
UniProt
View information about CDKN2A on UniProt.org

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