Purified anti-MMP8 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3206	1

规格

价格

库存

100µg

￥ 3206

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human MMP-8, amino acids (Phe21-Gly467) (Accession# NP_002415.1), is expressed with a C-terminal His tag and a linker sequence in 293E cell lines.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
IHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per ml. For immunohistochemical staining on formalin-fixed paraffin-embedded tissue sections, the suggested use of this reagent is 0.5 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2617008 (BioLegend Cat. No. 688002)

Structure: 467 amino acids, SDS-PAGE apparent molecular weight of Pro-MMP8 is 65-75 kD and Mature MMP8 is 55-60 kD. Consists of a prodomain that is cleaved upon activation, a catalytic domain, a hinge region and a carboxyl terminal domain with hemopexin-like repeats
Distribution: Neutrophils, macrophages, and monocytes.
Interaction: Collagen type I, II, and III, gelatin, proteoglycans, fibronectin, aggrecan, substance P, serpins, ?-casein, and angiotensin.
Cell Type: Neutrophils, Macrophages, Monocytes
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Neuroinflammation, Neuroscience
Molecular Family: Enzymes and Regulators
Antigen References: 1. Nagase H, Woessner JF Jr. 1999. J. Biol. Chem. 274:21491.
2. Gill SE, Parks WC. 2008. Int. J. Biochem. Cell Biol. 40:1334.
3. Mattey DL, et al. 2012. Arthritis Res. Ther. 14:R204.
4. Fang C, et al. 2013. Cardiovasc. Res. 99:146.
5. Lempinen M, et al. 2013. Ann. Med. 45:482.
6. Sommer K, et al. 2013. PLoS One 8:e73992.
Gene ID: 4317 View all products for this Gene ID
UniProt: View information about MMP-8 on UniProt.org