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Purified anti-PPARγ Antibody
产品名称：
Purified anti-PPARγ Antibody
产品类别：
抗体
产品编号：
683402
产品应用：
683402
[价格]
规格 价格 库存
100µg ￥ 4032 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Synthetic PPARγ peptide conjugated to KLH (CETDMSLHPLLQEIYKDLY)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g/ml. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Chevrier S, et al. 2021. Cell Reports Medicine. 2(1):100166. PubMed
RRID
AB_2572020 (BioLegend Cat. No. 683402)

Antigen Details

Structure
505 amino acids with an approximate molecular weight of 57.6 kD. Contains two zinc finger domains responsible for DNA binding.
Distribution

Nucleus.

Function
PPARγ is a nuclear receptor that modulates transcription of its target genes. It plays crucial roles in inflammation, energy homeostasis, and adipocyte differentiation.
Interaction
PPARγ interacts with FOXO1, RXRA, PPARBP, ASXL1, ASXL2, DNTTIP2, FAM120B, MAP2K1/MEK1, NR0B2, PDPK1, PRDM16, PRMT2 and TGFB1I1.
Biology Area
Cell Biology, Transcription Factors
Molecular Family
Nuclear Markers
Antigen References

1. Majithia AR, et al. 2014. Proc. Natl. Acad. Sci. USA 111:13127.
2. Aprile M, et al. 2014. PPAR. Res. 2014:537865.
3. Pott S, et al. 2013. PLoS One 7:e48102.
4. Klemke M, et al. 2011. Cancer Genet. 204:334.
5. Folwaczny M, et al. 2011. Innate Immun. 17:541.
6. Fuentes P, et al. 2010. J. Endocrinol. 206:75.

Gene ID
5468 View all products for this Gene ID
UniProt
View information about PPARgamma on UniProt.org

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