APC anti-human Aiolos Antibody
- 产品名称：
- APC anti-human Aiolos Antibody
- 产品类别：
- 抗体
- 产品编号：
- 371011
- 产品应用：
- 371011
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2156 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial Aiolos recombinant protein (1-130aa) expressed in E. Coli
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended.
This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).
- RRID
- AB_2910418 (BioLegend Cat. No. 371011) AB_2910418 (BioLegend Cat. No. 371012)
- Structure
- 58kD, zinc finger protein
- Distribution
-
T and B lymphocytes
- Function
- Hematopoetic-specific transcriptional activator and chromatin remodeler
- Interaction
- Forms heterodimers with Ikaros family members IKZF4 and IKZF5
- Cell Type
- B cells, T cells
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Chromatin Remodeling/Epigenetics, Immunology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
- Zhuang Y, et al. 2015. Oncol?Rep. 33:1319-25.
- Ma S, et al. 2008. Blood. 111:1396-403.
- Billot K, et al. 2010. Leuk?Res. 34:289-93.
- Morgan B, et al. 2004. EMBO J. 16:2004.
- Wang JH, et al. 1998. Immunity. 9:543-53.
- Hosokawa Y, et al. 1999. Genomics. 61:326-9.
- Gene ID
- 22806 View all products for this Gene ID
- UniProt
- View information about Aiolos on UniProt.org
