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Purified anti-DDX5 Antibody
产品名称:
Purified anti-DDX5 Antibody
产品类别:
抗体
产品编号:
661302
产品应用:
661302
[价格]
规格 价格 库存
100µg ¥ 3710 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial human DDX5 recombinant protein (482-614 a.a.) expressed in E. coli.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per ml. For immunocytochemistry, the suggested use of this reagent is 2.0 - 10 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2563942 (BioLegend Cat. No. 661302)

Antigen Details

Structure
614 amino acids, predicted molecular weight of 69 kD. Contains a DEAD box domain, a helicase domain, and a transactivation domain.
Distribution

Nucleus.

Function
DDX5 is an ATP-dependent RNA helicase, regulating RNA processing and ribosome biogenesis. DDX5 is also involved in transcription by acting as a transcriptional coactivator or a repressor.
Interaction
DDX5 interacts with DDX17, RBM4, AGO1, AGO2, ESR1, p300, RUNX2, and HDAC1.
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Transcription Factors
Antigen References

1. Iyer RS, et al. 2014. Cell Cycle. 13:1413.
2. Samaan S, et al. 2014. Nucleic Acids Res. 42:2197.
3. Fuller-Pace FV. 2013. Biochim. Biophys. Acta. 1829:756.
4. Wang D, et al. 2012. Mol. Cell Proteomics. 11:M111.011932.
5. Saporita AJ, et al. 2011. Cancer Res. 71:6708.
6. Clark EL, et al. 2008. Cancer Res. 68:7938.

Gene ID
1655 View all products for this Gene ID
UniProt
View information about DDX5 on UniProt.org

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