Purified anti-HDAC4 Antibody
- 产品名称:
- Purified anti-HDAC4 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 676801
- 产品应用:
- 676801
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial human HDAC4 recombinant protein (529 - 651 a.a.) expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone 14A9C47 weakly cross-reacts?with mouse HDAC4.
This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).
In some experimental systems a non-specific band may be observed at ~75kD.
?
- RRID
- AB_2861052 (BioLegend Cat. No. 676801) AB_2565722 (BioLegend Cat. No. 676802)
- Structure
- 1084 amino acids with a predicted molecular weight of 119 kD. Contains a histone deacetylase region and a N-terminal homodimerization domain.
- Distribution
-
Cytoplasm and nucleus.
- Interaction
- CDKN2A forms a homodimer and interacts with HDAC7, MEF2C, BTBD14B, AHRR, NR2C1, adn 14-3-3.
- Biology Area
- Cell Biology, Chromatin Remodeling/Epigenetics, Transcription Factors
- Antigen References
-
1. Tong JK, et al. 1998. Nature 395:917.
2. Grunstein M.? 1997. Nature 389:349.
3. Wolffe AP. 1996. Science 272:371.
4. Lee DY, et al. 1993. Cell 72:73.
5. Wang AH, et al. 2001. Mol. Cell Biol. 21:5992.
6. Bertos NR, et al. 1999. Mol. Cell Biol. 11:7816.
- Gene ID
- 9759 View all products for this Gene ID
- UniProt
- View information about HDAC4 on UniProt.org