PE anti-SOX2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 2142	1

Product Details

Verified Reactivity

Human, Mouse

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Full length human SOX recombinant protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).

Product Citations

Lee K, et al. 2019. Cell Rep. 28:382. PubMed
Wang C, et al. 2020. British Journal of Pharmacology. 177(13):3009-3023. PubMed
Radhakrishnan S, et al. 2019. Mol Med Rep. 20:813. PubMed
Yang Z, et al. 2020. Sci Rep. 17757:10. PubMed
Mirzaei R, et al. 2021. Sci Adv. 7:eabh2148. PubMed

RRID

AB_2562852 (BioLegend Cat. No. 656103) AB_2562853 (BioLegend Cat. No. 656104)

Structure: 317 amino acids, predicted molecular weight of 34 kD, contains a HMG box domain responsible for DNA binding
Distribution: Nucleus
Function: Transcription factor that regulates the expression of the genes involved in embryonic development
Interaction: Interacts with FGFR1, SOX3, and ZSCAN10
Cell Type: Mesenchymal Stem Cells, Embryonic Stem Cells, Neural Stem Cells
Biology Area: Cell Biology, Cell Cycle/DNA Replication, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells, Transcription Factors
Antigen References: 1. Rizzino A. 2009. Wiley Interdiscip. Rev. Syst. Biol. Med. 1:228.
2. Stolzenburg S, et al. 2012. Nucleic Acids Res. 40:6725.
3. Lai YS, et al. 2012. Proc. Natl. Acad. Sci. USA. 109:3772.
4. Jeong CH, et al. 2010. Stem Cells?28:2141.
5. Xiang R, et al. 2011. Br. J. Cancer 104:1410.
6. Card DA, et al. 2008. Mol. Cell Biol. 28:6426.
Gene ID: 6657 View all products for this Gene ID
UniProt: View information about SOX2 on UniProt.org