Direct-Blot™ HRP anti-HDAC2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µL	￥ 4760	1

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Human HDAC2 peptide (471-488 a.a.) conjugated to KLH.
Formulation: This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation: The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application: WB -?Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested dilution is 1:5000-1:50000. The optimal dilution should be determined by titration for each individual assay of interest.

25 ?l and 100 ?l of Direct-Blot? HRP antibody can be used for approximately 5 and 20 Western blots, respectively, at the recommended concentration/dilution.
RRID: AB_2687039 (BioLegend Cat. No. 680105)

Structure: 488 amino acids with a predicted molecular weight of 55.4 kD. It contains a histone deacetylase domain.
Distribution: Nucleus.
Function: HDAC2 is a histone deacetylase responsible for the deacetylation of ε-amino acid group of lysine residues on the N-terminal tail of core histones. Forms of complex with transcription factors and acts as a transcriptional co-repressor.
Interaction: Forms histone deacetylase complexes with HDAC1, RBBP4, and RBBP7. Interacts with GFI1, SNW1, HDAC7, PRDM6, SAP30, SETDB1, SUV39H1, H2AFY, ATR, CBFA2T3, BCL-6, DNMT1, MINT, HDAC10, HCFC1, NRIP1, KDM4A, and PELP1.
Biology Area: Cell Biology, Chromatin Remodeling/Epigenetics, Transcription Factors
Antigen References: 1. Winter M,?et al.?2013.?EMBO J.?32:3176.
2. Ma P,?et al.?2013.?PLoS Genet.?9:e1003377.
3. Kurita M,?et al.?2012.?Nat. Neurosci.?15:1245.
4. Segre CV,?et al.?2011.?J. Biomed. Biotechnol.?2011:690848.
5. Brunmeir R,?et al.?2009.?Int. J. Dev. Biol.?53:275.
6. Guan JS,?et al.?2009.?Nature?459:55.
Gene ID: 3066 View all products for this Gene ID
UniProt: View information about HDAC2 on UniProt.org