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Purified anti-CARD9 Antibody
产品名称:
Purified anti-CARD9 Antibody
产品类别:
抗体
产品编号:
679102
产品应用:
679102
[价格]
规格 价格 库存
100µg ¥ 4354 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CARD9 peptide (LRKMQKGWRQGEEDRENT) conjugated to KLH.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. For immunocytochemistry, a concentration range of 1.0 - 5.0 ?g/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2566076 (BioLegend Cat. No. 679102)

Antigen Details

Structure
536 amino acids with a predicted molecular weight of 62.2 kD. Contains a N-terminal CARD domain responsible for interacting with other CARD-containing proteins.
Distribution

Cytoplasm.

Function
CARD9 is a scaffold molecule that mediates the assembly of a signaling complex containing BCL10 and MALT1. CARD9 plays an important role in processes such as apoptosis, NF-κB activation, and host defense against pathogens.
Interaction
Interacts with BCL10, NOD2, RIPK2, and VHL.
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity, Neuroscience, Signal Transduction
Antigen References

1. Jia XM, et al. 2014. J. Exp. Med. 211:2307.
2. Roth S, et al. 2014. Nat. Immunol. 15:538.
3. Yamamoto H, et al. 2014. Infect Immun. 4:1606.
4. Shenderov K, et al. 2013. J. Immunol. 190:5722.
5. Drummond RA, et al. 2011. Eur. J. Immunol. 41:276.
6. Goodridge HS, et al. 2009. J. Immunol. 182:1146.

Gene ID
64170 View all products for this Gene ID
UniProt
View information about CARD9 on UniProt.org

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