Purified anti-Artemis Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3542	1

规格

价格

库存

100µg

￥ 3542

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Partial human anti-Artemis recombinant protein (347-692 a.a.) expressed in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Clone 13A9C90 recognizes both human and mouse Artemis; Clone 15E7C90 only recognizes human Artemis
RRID: AB_2632771 (BioLegend Cat. No. 692902)

Structure: 692 amino acids with a predicted molecular weight of 78.4 kD. Four isoforms produced by alternative splicing.
Distribution: Nucleus.
Function: Artemis is a nuclear protein exhibiting single-strand-specific 5'-3' exonuclease activity and endonuclease activity. It plays crucial roles in V(D)J recombination and DNA repair.
Interaction: Interacts with ATM, BRCA1, PRKDC and TP53BP1.
Cell Type: Mesenchymal Stem Cells
Biology Area: Cell Biology, DNA Repair/Replication, Stem Cells
Antigen References: 1. Chang HH, Lieber MR. 2016. Nucleic Acids Res. 44:4991.
2. Volk T, et al. 2015. Hum Mol Genet. 24:7361.
3. Waide EH, et al. 2015. J Immunol. 195:3171.
4. Lee PP, et al. 2013. Clin Immunol. 149:464.
5. K?cher S, et al. 2012. Nucleic Acids Res. 40:8336.
6. Beucher A, et al. 2009. EMBO J. 28:3413.
Gene ID: 64421 View all products for this Gene ID
UniProt: View information about Artemis on UniProt.org