首页 > 抗体蛋白 > 抗体
Purified anti-HDAC7 Antibody
产品名称:
Purified anti-HDAC7 Antibody
产品类别:
抗体
产品编号:
683502
产品应用:
683502
[价格]
规格 价格 库存
100µg ¥ 4354 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Synthetic HDAC7 peptide conjugated to KLH (1-17 a.a.)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ChIP - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. For ChIP applications, the suggested dilution is 1:50-1:100 by volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2572024 (BioLegend Cat. No. 683502)

Antigen Details

Structure
952 amino acids with a predicted molecular weight of 102.9 kD. Contains a histone deacetylase domain.
Distribution

Cytoplasm and the nucleus.

Function
HDAC7 mediates deacetylation of lysine residues in the N-terminal tails of core histones. It plays important roles in the regulation of T-cell differentiation and development of muscle and blood vessel.
Interaction
HDAC7 interacts with HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, FOXP3, KAT5, EDNRA, KDM5B, NCOR1, NCOR2, SIN3A, SIN3B, RBBP4, RBBP7, MTA1L1, SAP30 and MBD3.
Biology Area
Cell Biology, Chromatin Remodeling/Epigenetics, Neuroscience, Transcription Factors
Antigen References

1. Barneda-Zahonero B, et al. 2013. PLoS Genet. 9:e1003503.
2. Pham L, et al. 2011. J. Biol. Chem. 286:12056.
3. Li S, et al. 2011. Mol. Cancer 10:18.
4. Gao C, et al. 2010. Biochim. Biophys. Acta. 1803:1186.
5. Margariti A, et al. 2009. J. Cell. Sci. 122:460.
6. Parra M, et al. 2007. Genes Dev. 21:638.

Gene ID
51564 View all products for this Gene ID
UniProt
View information about HDAC7 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线