Purified anti-PACSIN1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 4032	1

规格

价格

库存

100µg

￥ 4032

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Partial mouse PACSIN1 recombinant protein (26-275 a.a.) expressed in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
IP - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per ml.?For immunoprecipitation, the suggested use of this reagent is 10-30 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2563628 (BioLegend Cat. No. 660902)

Structure: 441 amino acids, predicted molecular weight of 51 kD. Contains a N-terminal F-BAR domain and a C-terminal SH3 domain.
Distribution: Cytoplasm and cell membrane of neurons. Expressed highly in the brain, lower expression in liver, heart, and pancreas.
Function: PACSIN1 is a neuron-specific protein, involved in the processes of endocytosis and rearrangement of the microtubule cytoskeleton.
Interaction: Forms a homodimer or heterodimers with other PACSIN family members. Interacts with synaptojanin 1, WASP, and dynamin-1 via the SH3 domain.
Cell Type: Dendritic cells
Biology Area: Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Signal Transduction
Antigen References: 1. Liu Y, et al. 2012. J. Biol. Chem. 287:39911.
2. Esashi E, et al. 2012. Eur. J. Immunol. 42:573.
3. Bai X, et al. 2010. Acta. Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 66:73.
4. Pérez-Ota?o I, et al. 2006. Nat. Neurosci. 9:611.
5. Kessels MM, et al. 2004. J. Cell Sci. 117:3077.
6. Wasiak S, et al. 2001. J. Biol. Chem. 276:26622.
Gene ID: 23969 View all products for this Gene ID
UniProt: View information about PACSIN1 on UniProt.org