Purified anti-mouse CD300LG (Nepmucin) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3948	1

规格

价格

库存

100µg

￥ 3948

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Nepmucin-Fc fusion protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
EM - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications for the relevant formats include: immunoelectron microscopy of peripheral LN HEVs¹.

Application References (PubMed link indicates BioLegend citation)

Umemoto E, et al. 2006. J. Exp. Med. 203:1603. (EM)
Jin S, et al. 2008. FEBS Lett. 582:3018.
Umemoto E, et al. 2011. Crit. Rev. Immunol. 31:147.
Umemoto E, et al. 2013. PLoS One 8:e83681.

RRID

AB_2562968 (BioLegend Cat. No. 147102)

Antigen Details

Structure: Sialomucin, member of the CD300 antigen like family, 50-95 kD. 1 IgV like domain, 1 mucin like domain. Four isoforms produced by alternative splicing.
Distribution: Expressed on high endothelial venules (HEVs) from lymph nodes but absent on HEVs from Peyer's patches, some myeloid cell lines.
Function: Mediator of lymphocyte adhesion and rolling on HEVs, possible role in transcytosis across the capillary endothelium.
Ligand/Receptor: L-selectin.
Biology Area: Cell Adhesion, Cell Biology, Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Takatsu H, et al. 2006. Biochem. Biophys. Res. Commun. 348:183.
2. Umemoto E, et al. 2006. J. Exp. Med. 203:1603.
3. Umemoto E, et al. 2011. Crit. Rev. Immunol. 31:147.
Gene ID: 52685 View all products for this Gene ID
UniProt: View information about CD300LG on UniProt.org

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