FITC anti-mouse CD8b Antibody
- 产品名称：
- FITC anti-mouse CD8b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 126605
- 产品应用：
- 126605
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen tissue sections.
- Application References
(PubMed link indicates BioLegend citation) -
- McNical AM, et al. 2007. Eur. J. Immunol. 37:1634.
- Product Citations
-
- Misumi I et al. 2019. Cell Rep. 27(5):1387-1396 . PubMed
- Misumi I et al. 2019. Cell Rep. 27(2):514-524 . PubMed
- LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
- Mardomi A, et al. 2021. J Cell Physiol. 236:6328. PubMed
- Canto F, et al. 2016. Sci Rep. 6:28573. PubMed
- Bianchi JJ, et al. 2019. Cell Rep. 27:2847. PubMed
- Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
- LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
- Moon S, et al. 2021. J Exp Med. 218:. PubMed
- Nelson CE et al. 2019. Cell Rep. 28(12):3092-3104 . PubMed
- Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
- Lee-Chang C, et al. 2021. J Exp Med. 218:. PubMed
- Nakagawa Y, et al. 2012. Int Immunol. 25:11. PubMed
- Wells AC et al. 2017. eLife. 6 pii: e26398. PubMed
- Viaud M, et al. 2020. Cell Reports. 30(10):3397-3410. PubMed
- Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
- RRID
- AB_961293 (BioLegend Cat. No. 126605) AB_961295 (BioLegend Cat. No. 126606)
- Structure
- Ig superfamily, CD8β chain, 34 kD
- Distribution
-
Majority of thymocytes, cytotoxic T cell subsets
- Function
- Co-receptor of TCR
- Ligand/Receptor
- MHC class I
- Cell Type
- T cells, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1.Barclay A, et al. 1997. The Leukocyte antigen Facts Book Academic Press.
2. Zamoyska R. 1994. Immunity 1:243-246.
3. Ellmeier W, et al. 1999. Annu. Rev Immunol 17:523.
4. Ledbetter JA, et al. 1981. J. Exp. Med. 153:1503.
- Gene ID
- 12526 View all products for this Gene ID
- UniProt
- View information about CD8b on UniProt.org
