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PE anti-human CD13 Antibody
产品名称:
PE anti-human CD13 Antibody
产品类别:
抗体
产品编号:
301703
产品应用:
301703
[价格]
规格 价格 库存
25tests ¥ 1372 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
Baboon, Chimpanzee, Cotton-topped Tamarin
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: inhibition of tumor-cell invasion and blocking of aminopeptidase activities2,3, and immunohistochemical staining of acetone-fixed frozen tissue sections5. WM15 does not?recognize formalin-fixed or paraffin-embedded tissue sections5. The LEAF? purified antibody (Endotoxin < 0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 301708). For highly sensitive assays, we recommend Ultra-LEAF? purified antibody (Cat. No. 301723 and 301724) with a lower endotoxin limit than standard LEAF? purified antibodies (Endotoxin < 0.01 EU/?g).

Application References

(PubMed link indicates BioLegend citation)
  1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  2. Saiki I, et al. 1993. Int J Cancer. 54:137. (Block)
  3. Rosenzwajg M, et al. 2000. Blood 95:453. (Block)
  4. Kawase M, et al. 2008. J Virol. 83:712. (Block) PubMed
  5. Di Matteo P, et al. 2011. J. Histochem. Cytochem. 59:47. (IHC)
Product Citations
  1. Valentijn A, et al. 2013. Hum Reprod. 28:2695. PubMed
  2. Zhao M, et al. 2021. Frontiers in Cell and Developmental Biology. 9:652972. PubMed
  3. Melzer C, et al. 2020. Int J Mol Sci. :21. PubMed
  4. Xin Y, et al. 2021. Stem Cell Res Ther. 49:12. PubMed
  5. Gill D, et al. 2022. Elife. 11:. PubMed
  6. Man L, et al. 2020. Cell Reports. 32(6):108027. PubMed
  7. Ma X, et al. 2022. Front Oncol. 12:855570. PubMed
  8. Boxx G, et al. 2010. Infect Immun. 78:1250. PubMed
  9. Qi J, et al. 2022. Nat Commun. 13:1742. PubMed
  10. Li F, et al. 2022. Front Pharmacol. 13:1001552. PubMed
  11. Wu L, et al. 2018. Oncol Lett. 15:9507. PubMed
  12. Yao J, et al. 2022. Front Pharmacol. 13:876076. PubMed
  13. Kobayashi H, et al. 2020. Cell Reports. 28(1):145-158.e9.. PubMed
  14. Zhang H, et al. 2017. Oncogene. 10.1038/onc.2016.512. PubMed
  15. Zeng Y et al. 2019. Immunity. 51(5):930-948 . PubMed
  16. Smith-Díaz CC, et al. 2021. Front Oncol. 11:709543. PubMed
  17. Siciliano C, et al. 2016. Stem Cell Res. 17: 342-351. PubMed
  18. Qu M, et al. 2021. Frontiers in Oncology. 11:659720. PubMed
  19. Mpakou V, et al. 2021. Exp Ther Med. 1.010416667. PubMed
  20. Bombelli S,et al. 2017. Am J Pathol. . 10.1016/j.ajpath.2017.09.012. PubMed
RRID
AB_314179 (BioLegend Cat. No. 301703) AB_314180 (BioLegend Cat. No. 301704)

Antigen Details

Structure
Zinc metallopeptidase, type II integral membrane glycoprotein, 150-170 kD
Distribution

Granulocytes, monocytes, myeloid progenitors, endothelial and epithelial cells, granular lymphocyte subset

Function
Zinc-binding metalloproteinase, antigen processing, cleaves MIP-1 chemokine
Ligand/Receptor
Coronavirus receptor
Cell Type
Endothelial cells, Epithelial cells, Granulocytes, Hematopoietic stem and progenitors, Lymphocytes, Mesenchymal Stem Cells, Monocytes, Neutrophils
Biology Area
Immunology, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Shipp M, et al. 1993. Blood 82:1052.
2. Larsen S, et al. 1996. J. Exp. Med. 184:183.

Gene ID
290 View all products for this Gene ID
UniProt
View information about CD13 on UniProt.org

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