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Purified anti-Lamin A/C Antibody
产品名称:
Purified anti-Lamin A/C Antibody
产品类别:
抗体
产品编号:
600001
产品应用:
600001
[价格]
规格 价格 库存
25µg ¥ 1414 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
GST fused to C-terminal fragment of Lamin A (amino acid residues 422-664)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

WL4G10 does not recognize mouse Lamin A or C.

WL4G10 failed to immunoprecipitate Lamin A or C from HeLa lysates.

During PD testing for ICC applications, WL4G10 staining of PFA-fixed HeLa cells was compatible with both Methanol and Triton X-100 permeabilization methods; observed staining was slightly better with Triton X-100 permabilization.

RRID
AB_2810655 (BioLegend Cat. No. 600001) AB_2810656 (BioLegend Cat. No. 600002)

Antigen Details

Structure
Lamin A is a 664 amino acid protein with a predicted molecular weight of 74 kD. Lamin C is a 572 amino acid protein with a predicted molecular weight of 65 kD.
Distribution

Ubiquitously expressed/Nucleoplasmic side of inner nuclear membrane

Function
Fibrous component of nuclear lamina, provides framework for nuclear envelope, may interact with chromatin
Cell Type
Neurons
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers, Western Blot Controls
Molecular Family
Nuclear Markers, Organelle Markers
Gene ID
4000 View all products for this Gene ID
UniProt
View information about Lamin A/C on UniProt.org

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