Purified anti-Hsp70 Antibody
- 产品名称：
- Purified anti-Hsp70 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 648001
- 产品应用：
- 648001
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Hsp70 protein from HeLa cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB, ICFC - Quality tested
ICC - Verified?
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per ml. For immunocytochemistry, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Fong J, et al. 2015. EMBO J. 34: 2775 - 2788. PubMed
- Zhang K, et al. 2021. Neuron. 109(12):1949-1962.e6. PubMed
- V?tsveen TK, et al. 2018. J Hematol Oncol. 11:23. PubMed
- Harris IS et al. 2019. Cell metabolism. 29(5):1166-1181 . PubMed
- Hashimoto M, et al. 2022. Front Neurosci. 16:948517. PubMed
- RRID
- AB_2028531 (BioLegend Cat. No. 648001) AB_2264228 (BioLegend Cat. No. 648002)
- Structure
- Hsp proteins are the most conserved proteins present in both prokaryotes and eukaryotes. Human HSp70 contains multiple isoforms. Hsp70s consisit of three structural domains, a 44Kd amino-terminal ATPase domain (NBD), followed by an 18 Kd substrate
- Distribution
-
Ubiquitous, cytoplasmic and nuclear
- Function
- Molecular chaperrones assisting in the folding of proteins and preventing protein aggregation
- Biology Area
- Cell Biology, Neurodegeneration, Neuroinflammation, Neuroscience, Protein Trafficking and Clearance
- Antigen References
-
1. Sharma D, et al. 2009. Protein Peptide Lett. 16:571.
2. Johnson JD, et al. 2006. J. Leuk. Biol. 79:425.
3. Bukau B, et al. 1998. Cell 92:351.
- Gene ID
- 3308 View all products for this Gene ID
- UniProt
- View information about Hsp70 on UniProt.org
