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Alexa Fluor® 488 anti-Hsp70 Antibody
产品名称:
Alexa Fluor® 488 anti-Hsp70 Antibody
产品类别:
抗体
产品编号:
648003
产品应用:
648003
[价格]
规格 价格 库存
25tests ¥ 2310 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Hsp70 protein from HeLa cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser
Blue Laser (488 nm)
Product Citations
  1. Salybekov AA, et al. 2021. Front Cardiovasc Med. 8:754254. PubMed
  2. Mouratidis PXE, et al. 2021. Int J Hyperthermia. 38:1443. PubMed
  3. Pascual-Pasto G, et al. 2022. J Immunother Cancer. 10:. PubMed
  4. Kırbaş OK, et al. 2019. Sci Rep. 9:19159. PubMed
RRID
AB_2119539 (BioLegend Cat. No. 648003) AB_2119537 (BioLegend Cat. No. 648004)

Antigen Details

Structure
Hsp proteins are the most conserved proteins present in both prokaryotes and eukaryotes. Human HSp70 contains multiple isoforms. Hsp70s consisit of three structural domains, a 44Kd amino-terminal ATPase domain (NBD), followed by an 18 Kd substrate
Distribution

Ubiquitous, cytoplasmic and nuclear

Function
Molecular chaperrones assisting in the folding of proteins and preventing protein aggregation
Biology Area
Cell Biology, Neurodegeneration, Neuroinflammation, Neuroscience, Protein Trafficking and Clearance
Antigen References

1. Sharma D, et al. 2009. Protein Peptide Lett. 16:571.
2. Johnson JD, et al. 2006. J. Leuk. Biol. 79:425.
3. Bukau B, et al. 1998. Cell 92:351.

Gene ID
3308 View all products for this Gene ID
UniProt
View information about Hsp70 on UniProt.org

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