Purified anti-human CD61 Antibody
- 产品名称：
- Purified anti-human CD61 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 336402
- 产品应用：
- 336402
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
CyTOF?, ICC - Verified
IHC-F, WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: Western blotting and immunohistochemical staining of frozen tissue sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Davies J, et al. 1989. J. Cell Biol. 109:1817.
- Roberts M, et al. 2004. Mol. Cell. Biol. 24:1505.
- Ciarlet M, et al. 2002. J. Virol. 76:1109.
- Product Citations
-
- Azizi E et al. 2018. Cell. 174(5):1293-1308 e36. PubMed
- Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
- Wastyk HC, et al. 2021. Cell. 184(16):4137-4153.e14. PubMed
- Hartmann FJ, et al. 2019. Cell Rep. 28:819. PubMed
- Li F, et al. 2022. iScience. 25:105147. PubMed
- RRID
- AB_1227584 (BioLegend Cat. No. 336402)
- Structure
- Type I integral glycoprotein, integrin family, associates with CD41 (gpIIb) forming CD41/CD61 complex or with CD51 (integrin αV) forming CD51/CD61 complex, 90 kD
- Distribution
-
CD41/CD61 complex is expressed on platelets and megakaryocytes; CD51/CD61 complex is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells
- Function
- Adhesion, platelet activation and aggregation
- Ligand/Receptor
- Fibronectin, vitronectin, vWF
- Cell Type
- Fibroblasts, Megakaryocytes, Osteoclasts, Platelets
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers.
- Gene ID
- 3690 View all products for this Gene ID
- UniProt
- View information about CD61 on UniProt.org
