PE anti-mouse CD73 Antibody
- 产品名称：
- PE anti-mouse CD73 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 127205
- 产品应用：
- 127205
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CHO cells transfected with mouse CD73
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Yamshita Y, et al 1998. Eur. J. Immunol. 28:2981.
- Bentley JK, et al. 2010. Respir. Res. 11:127. (IHC-P)
- Product Citations
-
- Li L, et al. 2017. FASEB J. 31:1067. PubMed
- Vasanthakumar A, et al. 2020. Nature. 579:581. PubMed
- Fan C, et al. 2020. Stem Cell Res Ther. 0.765277778. PubMed
- Chen ELY, et al. 2021. Cell Rep. 35:109227. PubMed
- Xu L et al. 2017. Immunity. 47(3):538-551 . PubMed
- Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
- Ortín-Martínez A, et al. 2021. EMBO J. 40:e107264. PubMed
- Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
- Gabriel SS, et al. 2021. Immunity. 54(8):1698-1714.e5. PubMed
- Santini MP, et al. 2020. Cell Rep. 30:555. PubMed
- Soleimani A, et al. 2022. Sci Rep. 12:10423. PubMed
- Xu C, et al. 2021. Cell Reports. 35(11):109235. PubMed
- Zilionis R et al. 2019. Immunity. 50(5):1317-1334 . PubMed
- Timilshina M, et al. 2020. Cell Reports. 27(10):2948-2961.e7.. PubMed
- RRID
- AB_1089065 (BioLegend Cat. No. 127205) AB_2154094 (BioLegend Cat. No. 127206)
- Structure
- 69 kD GPI-anchored surface protein
- Distribution
-
Positive on most CD11b+ myeloid cells in bone marrow, but not on CD11b+ peripheral cells; a large proportion of CD4+ and CD8+ splenic T cells express CD73
- Function
- A nucleotidase catalyzing the dephosphorylation of extracellular nucleoside 5' monophosphates
- Ligand/Receptor
- Nucleoside 5' monophosphate
- Cell Type
- B cells, Mesenchymal Stem Cells, Tregs
- Biology Area
- Costimulatory Molecules, Immunology, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. Yamashita Y, et al 1998. Eur. J. Immunol. 28:2981.
2. Resta R, et al. 1998. Immunol. Rev. 161:95.
- Regulation
- Expression is regulated by the development and maturation of leukocytes
- Gene ID
- 23959 View all products for this Gene ID
- UniProt
- View information about CD73 on UniProt.org
