APC anti-mouse CD73 Antibody
- 产品名称：
- APC anti-mouse CD73 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 127209
- 产品应用：
- 127209
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CHO cells transfected with mouse CD73
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Yamshita Y, et al 1998. Eur. J. Immunol. 28:2981.
- Bentley JK, et al. 2010. Respir. Res. 11:127. (IHC-P)
- Product Citations
-
- Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
- Moor AE et al. 2018. Cell. 175(4):1156-1167 . PubMed
- Hirata Y et al. 2018. Cell stem cell. 22(3):445-453 . PubMed
- Sarin S et al. 2018. Neuron. 98(1):109-126 . PubMed
- Kleine Holthaus SM, et al. 2018. Mol Ther. 26:1343. PubMed
- Hou M, et al. 2020. Stem Cell Res Ther. 11:55. PubMed
- Rebekka K Schneider et al. 2017. Cell stem cell. 20(6):785-800 . PubMed
- Becher J, et al. 2018. Dev Cell. 47:592. PubMed
- Ortín-Martínez A, et al. 2021. EMBO J. 40:e107264. PubMed
- Shen YC, et al. 2021. Nat Commun. 12:3876. PubMed
- Huang D, et al. 2020. Nat Commun. 4.520833333. PubMed
- Ben-Moshe S, et al. 2019. Nat Metab. 1:899. PubMed
- Shevach H 2016. J Immunol. 196: 1517 - 1528. PubMed
- Vieira JMF, et al. 2022. PLoS One. 17:e0272962. PubMed
- RRID
- AB_11219400 (BioLegend Cat. No. 127209) AB_11218786 (BioLegend Cat. No. 127210)
- Structure
- 69 kD GPI-anchored surface protein
- Distribution
-
Positive on most CD11b+ myeloid cells in bone marrow, but not on CD11b+ peripheral cells; a large proportion of CD4+ and CD8+ splenic T cells express CD73
- Function
- A nucleotidase catalyzing the dephosphorylation of extracellular nucleoside 5' monophosphates
- Ligand/Receptor
- Nucleoside 5' monophosphate
- Cell Type
- B cells, Mesenchymal Stem Cells, Tregs
- Biology Area
- Costimulatory Molecules, Immunology, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. Yamashita Y, et al 1998. Eur. J. Immunol. 28:2981.
2. Resta R, et al. 1998. Immunol. Rev. 161:95.
- Regulation
- Expression is regulated by the development and maturation of leukocytes
- Gene ID
- 23959 View all products for this Gene ID
- UniProt
- View information about CD73 on UniProt.org
