APC anti-mouse Allergin-1 Antibody
- 产品名称：
- APC anti-mouse Allergin-1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 141807
- 产品应用：
- 141807
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Transfected cells expressing allergin-1-Flag
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Inhibits FcεRI-mediated degranulation in bone marrow-derived cultured mast cells1.?Additional reported applications (for the relevant formats) include: blocking1.
- Application References
(PubMed link indicates BioLegend citation) -
- Hitomi K, et al. 2010. Nat. Immunol. 11:601. (Block)
- RRID
- AB_2561403 (BioLegend Cat. No. 141807)
- Structure
- Single pass transmembrane protein of 60 kD; contains one Ig-like C2-like domain and one ITIM-like domain
- Distribution
-
Mast cells, dendritic cells, macrophages, neutrophils
- Function
- Inhibits IgE-mediated degranulation of mast cells
- Interaction
- PTPN6, PTPN11 and INPP5D
- Cell Type
- Dendritic cells, Macrophages, Mast cells, Neutrophils
- Biology Area
- Cell Biology, Immunology, Signal Transduction
- Antigen References
-
1. Hitomi K, et al. 2010. Nat. Immunol. 11:601.
2. Pirozzi G, et al. 1995. J. Immunol. 155:5811.
- Gene ID
- 380732 View all products for this Gene ID
- UniProt
- View information about Allergin-1 on UniProt.org
