PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1) Antibod
- 产品名称：
- PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1) Antibod
- 产品类别：
- 抗体
- 产品编号：
- 133623
- 产品应用：
- 133623
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse DNAM-1 transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Excitation Laser
- Blue Laser (488 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Dardalhon V, et al. 2005. J. Immunol. 175:1558
- Shirakawa J, et al. 2006. International Immunology 18(6):951-957
- RRID
- AB_2716084 (BioLegend Cat. No. 133623) AB_2716085 (BioLegend Cat. No. 133624)
- Structure
- 65 kd glycoprotein of a member of Ig super-family containing 2 immunoglobulin-like domains.
- Distribution
-
Expressed on majority of CD8+ and CD4+ T cells, NK cells, monocytes/macrophages and a subset of B cells. Reported to up-regulated on Th1 cells, but down-regulated in Th2 cells.
- Function
- Mediate cellular adhesion, involved in LFA-1 co-stimulatory signal for T cell differentiation and proliferation.
- Ligand/Receptor
- CD112 and CD155
- Cell Type
- T cells, NK cells, Monocytes, Macrophages, Th1, B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1 Tahara Hanaoka S, et al. 2006. Blood. 107:1491
2 Shibuya K et al. 2003. J. Exp. Med. 198:1829.
- Gene ID
- 225825 View all products for this Gene ID
- UniProt
- View information about CD226 on UniProt.org
