Purified anti-human CD11a Antibody
- 产品名称：
- Purified anti-human CD11a Antibody
- 产品类别：
- 抗体
- 产品编号：
- 350602
- 产品应用：
- 350602
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- HLA-DR CTL line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for relevant formats) include: immunoprecipitation1, 2. Note: the antibody TS2/4 recognizes the ?-propeller domain of CD11a and only immunoprecipitates the CD11a/CD18 complex.
- Application References
(PubMed link indicates BioLegend citation) -
- Huang C and Springer TA. 1997. P. Natl. Acad. Sci. USA 94:3162. (IP)
- Sanchez-Madrid F, et al. 1983. J. Exp. Med. 158:1785. (IP)
- Sanchez-Madrid F, et al. 1982. P. Natl. Acad. Sci. USA 79:7489. (FC)
- Product Citations
-
- Weulersse M, et al. 2020. Immunity. 53(4):824-839.e10. PubMed
- Lefort C, et al. 2012. Blood. 119:4275. PubMed
- Baumgart F, et al. 2016. Nat Methods. 10.1038/nmeth.3897. PubMed
- Nandagopal S, et al. 2022. Cancer Immunol Res. 10:245. PubMed
- RRID
- AB_10662540 (BioLegend Cat. No. 350602)
- Structure
- Integrin, type I transmembrane glycoprotein, noncovalently linked with integrin β2 (CD18) forms LFA-1, 170-180 kD
- Distribution
-
Leukocytes
- Function
- Adhesion, costimulation
- Ligand/Receptor
- ICAM-1(CD54), ICAM-2(CD102), ICAM-3(CD50)
- Cell Type
- Leukocytes, Tregs
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience, Costimulatory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Lub M, et al. 1995. Immunol. Today 16:479.
2. Parsons J. 1996. Curr. Opin. Cell Biol. 8:146.
- Gene ID
- 3683 View all products for this Gene ID
- UniProt
- View information about CD11a on UniProt.org
