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PE anti-human CD29 Antibody
产品名称:
PE anti-human CD29 Antibody
产品类别:
抗体
产品编号:
303003
产品应用:
303003
[价格]
规格 价格 库存
25tests ¥ 1400 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cow, Cynomolgus, Dog, Horse, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen tissue sections3,5, and activation of integrin ?14,7,8. The LEAF? purified antibody (Endotoxin <0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 303010). Clone TS2/16 recognizes epitope A2.10

Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
  2. Gutierrez-Lopez M, et al. 2003. J. Biol. Chem. 278:208.
  3. Hemler ME, et al. 1984. J. Immunol. 132:3011. (IHC, IP)
  4. Sanchez-Aparicio P, et al. 1994. J. Cell Biol. 126:271. (Activ)
  5. Frank NY, et al. 2005. Cancer Res. 65:4320. (IHC)
  6. Murga M, et al. 2005. Blood 105:1992. (FC) PubMed
  7. Porter JC and Hogg N. 1997. J. Cell Biol. 138:1437. (Activ)
  8. Conway RE, et al. 2006. Mol. Cell. Biol. 26:5310. (Activ)
  9. Wesseling J, et al. 1995. J. Cell. Biol. 129:255. (Dog Reactivity)
  10. Rubio G, et al. 2002. Cancer Immunol. Immunother. 51:130.
  11. Dong A, et al. 2015. J Biol Chem. 290:8016. PubMed
  12. Paebst F, et al. 2014. Cytometry A. 85(8):678-87. (Horse reactivity)
Product Citations
  1. Xin Y, et al. 2021. Stem Cell Res Ther. 49:12. PubMed
  2. Wu J, et al. 2020. Cell Res. 30:794. PubMed
  3. Zhang PP, et al. 2021. Anim Cells Syst (Seoul). 25:296. PubMed
  4. Nie SC, et al. 2022. Med Sci Monit. 28:e934511. PubMed
  5. Bach FC, et al. 2018. Oncotarget. 9:26507. PubMed
  6. Sima LE, et al. 2019. Mol Cancer Ther. 1.484027778. PubMed
  7. Zhang B, et al. 2022. Stem Cells Int. 2022:2236250. PubMed
  8. Sun Z, et al. 2022. Stem Cell Res Ther. 13:297. PubMed
  9. Saulnier N, et al. 2015. Osteoarthritis Cartilage. 23:122. PubMed
  10. Wu S, et al. 2020. Stem Cells Int. 2019:1515040. PubMed
  11. Bouafia A, et al. 2018. J Clin Invest. 129:1047. PubMed
  12. Kerr BA, et al. 2021. Experimental Cell Research. 399(2):112456. PubMed
  13. Goncharova V, et al. 2014. Stem Cells Trans Med. 3:229. PubMed
  14. Bi S, et al. 2020. Protein Cell. 0.79375. PubMed
  15. Singh N, et al. 2020. Mol Oncol. 14:974. PubMed
  16. Wang D, et al. 2020. J Cell Mol Med. 24:4212. PubMed
  17. Wang X, et al. 2021. Front Endocrinol (Lausanne). 12:666195. PubMed
  18. Karakas N, et al. 2020. PLoS One. 15:e0228510. PubMed
  19. Hopf A, et al. 2022. Bioengineering (Basel). 9:. PubMed
  20. Chen C, et al. 2013. Placenta. 34:913. PubMed
  21. Zhang Y, et al. 2019. Aging (Albany NY). 11:12641. PubMed
  22. Fu H, et al. 2021. Front Cell Dev Biol. 9:764109. PubMed
  23. Keshtkar S, et al. 2021. Stem Cells Int. 8857457:2020. PubMed
  24. Xu Y, et al. 2020. Stem Cells Int. 8894449:2020. PubMed
  25. Josson S, et al. 2010. Prostate. 71:232. PubMed
  26. Hsieh J, et al. 2013. Nucleic Acids Res. 41:9753. PubMed
  27. Witschen PM, et al. 2020. Cancers. 12(5):1325. PubMed
  28. He H, et al. 2019. J Cell Mol Med. 23:4139. PubMed
  29. Grosche L, et al. 2020. Viruses. 12:. PubMed
  30. Fu L, et al. 2019. PLoS Biol. 17:e3000201. PubMed
  31. Koh Y, et al. 2009. Prostate. 69:571. PubMed
  32. Suzuki D, et al. 2020. Stem Cell Reports. 14:49. PubMed
  33. Lin HT, et al. 2019. Int J Mol Med. 43:1085. PubMed
  34. Hornung A, et al. 2020. Biophys J. 118:565. PubMed
  35. Dong N, et al. 2022. World J Stem Cells. 14:556. PubMed
RRID
AB_314319 (BioLegend Cat. No. 303003) AB_314320 (BioLegend Cat. No. 303004)

Antigen Details

Structure
Integrin, type I glycoprotein, forms VLA-1 to VLA-6 heterodimers with CD49a-f (α16), also associates with CD51 (αV), and α7- α9, 130 kD
Distribution

Lymphocytes, monocytes, granulocytes (low), platelets, mast cells, fibroblasts, endothelial cells

Function
Cell-cell and cell-matrix interactions
Ligand/Receptor
VCAM-1, MAdCAM-1, ECM
Cell Type
Embryonic Stem Cells, Endothelial cells, Fibroblasts, Granulocytes, Lymphocytes, Mast cells, Mesenchymal Stem Cells, Monocytes, Platelets, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Hemler M. 1990. Annu. Rev. Immunol. 8:365.
2. Hynes R. 1992. Cell 69:11.

Gene ID
3688 View all products for this Gene ID
UniProt
View information about CD29 on UniProt.org

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