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APC anti-human CD29 Antibody
产品名称：
APC anti-human CD29 Antibody
产品类别：
抗体
产品编号：
303007
产品应用：
303007
[价格]
规格 价格 库存
25tests ￥ 2086 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cow, Cynomolgus, Dog, Horse, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen tissue sections3,5, and activation of integrin ?14,7,8. The LEAF? purified antibody (Endotoxin <0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 303010). Clone TS2/16 recognizes epitope A2.10

Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
  2. Gutierrez-Lopez M, et al. 2003. J. Biol. Chem. 278:208.
  3. Hemler ME, et al. 1984. J. Immunol. 132:3011. (IHC, IP)
  4. Sanchez-Aparicio P, et al. 1994. J. Cell Biol. 126:271. (Activ)
  5. Frank NY, et al. 2005. Cancer Res. 65:4320. (IHC)
  6. Murga M, et al. 2005. Blood 105:1992. (FC) PubMed
  7. Porter JC and Hogg N. 1997. J. Cell Biol. 138:1437. (Activ)
  8. Conway RE, et al. 2006. Mol. Cell. Biol. 26:5310. (Activ)
  9. Wesseling J, et al. 1995. J. Cell. Biol. 129:255. (Dog Reactivity)
  10. Rubio G, et al. 2002. Cancer Immunol. Immunother. 51:130.
  11. Dong A, et al. 2015. J Biol Chem. 290:8016. PubMed
  12. Paebst F, et al. 2014. Cytometry A. 85(8):678-87. (Horse reactivity)
Product Citations
  1. Mancuso RV, et al. 2020. British Journal of Pharmacology. 177(12):2696-2711.. PubMed
  2. Guney-Esken G, et al. 2021. Stem Cell Res Ther. 12:287. PubMed
  3. Wang T, et al. 2019. Mol Med Rep. 19:4719. PubMed
  4. Zhou X, et al. 2020. Cells. 9(4):. PubMed
  5. Sperber HS, et al. 2020. FASEB J. 14615:34. PubMed
  6. Kang DH, et al. 2021. Nat Commun. 12:5059. PubMed
  7. Chulpanova DS, et al. 2020. Bioengineering (Basel). 7:00. PubMed
  8. Sarkar TJ, et al. 2020. Nat Commun. 11:1545. PubMed
  9. Frazier T, et al. 2018. Adipocyte. 0.41875. PubMed
  10. Judson RN et al. 2018. Cell stem cell. 22(2):177-190 . PubMed
  11. Quarta M, et al. 2016. Nat Biotechnol. 10.1038/nbt.3576. PubMed
  12. Liu B, et al. 2017. Hum Cell. 30:51. PubMed
  13. Vishnoi M, et al. 2015. Sci Rep. 5: 17533. PubMed
  14. Velázquez–Avila M, et al. 2019. Leukemia. 33:1337. PubMed
  15. Yang C et al. 2019. Int J Mol Med. 43(3):1395-1405 . PubMed
  16. Murga M, et al. 2005. Blood. 105:1992. PubMed
  17. Eikmans M, et al. 2022. Front Immunol. 13:814019. PubMed
  18. Chulpanova DS, et al. 2021. Biology (Basel). 10:. PubMed
  19. Kitaeva KV, et al. 2022. Bioengineering (Basel). 9:. PubMed
  20. Guney-Esken G, et al. 2021. Methods Mol Biol. 2549:23. PubMed
  21. Hegewisch-Solloa E, et al. 2021. J Immunol. 207:950. PubMed
  22. Liao HQ, et al. 2021. Am J Reprod Immunol. 86:e13406. PubMed
  23. Huijskens M, et al. 2014. J Leukoc Biol. 96:1165. PubMed
  24. Ding S, et al. 2018. Sci Rep. 8:10808. PubMed
  25. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  26. Lu H, et al. 2020. Am J Reprod Immunol. 83:. PubMed
  27. Tabebordbar M, et al. 2021. Cell. 184:4919. PubMed
  28. Chen G, et al. 2015. J Endod. 41: 1091-1099. PubMed
RRID
AB_314323 (BioLegend Cat. No. 303007) AB_314324 (BioLegend Cat. No. 303008)

Antigen Details

Structure
Integrin, type I glycoprotein, forms VLA-1 to VLA-6 heterodimers with CD49a-f (α1-α6), also associates with CD51 (αV), and α7- α9, 130 kD
Distribution

Lymphocytes, monocytes, granulocytes (low), platelets, mast cells, fibroblasts, endothelial cells

Function
Cell-cell and cell-matrix interactions
Ligand/Receptor
VCAM-1, MAdCAM-1, ECM
Cell Type
Embryonic Stem Cells, Endothelial cells, Fibroblasts, Granulocytes, Lymphocytes, Mast cells, Mesenchymal Stem Cells, Monocytes, Platelets, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Hemler M. 1990. Annu. Rev. Immunol. 8:365.
2. Hynes R. 1992. Cell 69:11.

Gene ID
3688 View all products for this Gene ID
UniProt
View information about CD29 on UniProt.org

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