Pacific Blue™ anti-human CD2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3710	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with Pacific Blue? under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The suggested use of this reagent is ≤ 1.0 ?g per 10⁶ cells in 100 ?l volume or 100 ?l of whole blood. It is highly recommended that the reagent be titrated for optimal performance for each application.

* Pacific Blue? has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue? conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser

Violet Laser (405 nm)

Application Notes

Additional reported applications (for the relevant formats) include: blocking of T cell activation, and partial blocking of B cell costimulation². The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. Nos. 309235 & 309236).

Application References (PubMed link indicates BioLegend citation)

Schlossman S, et al. Eds.1995. Leucocyte Typing V Oxford University Press. New York.
Hughes CCW, et al. 1996. J. Biol. Chem. 271:5369.

Product Citations

Picot T, et al. 2018. Front Oncol. 8:109. PubMed
Romee R, et al. 2013. Blood. 121:3599. PubMed

RRID

AB_2073669 (BioLegend Cat. No. 309216)

Antigen Details

Structure: Ig superfamily, type I transmembrane glycoprotein, 50 kD
Distribution: T cells, NK cells, thymocytes, and thymic B cell subsets
Function: T cell activation, adhesion
Ligand/Receptor: CD58 (LFA-3), CD48, CD59, CD15
Cell Type: B cells, NK cells, T cells, Thymocytes
Biology Area: Costimulatory Molecules, Immunology
Molecular Family: CD Molecules
Antigen References: 1. Bell G, et al. 1995. J. Immunol. 155:2805.
2. Bierer B, et al. 1989. Annu. Rev. Immunol. 7:579.
3. Moingeon P, et al. 1989. Immunol. Rev. 111:111.
Gene ID: 914 View all products for this Gene ID
UniProt: View information about CD2 on UniProt.org

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