Purified anti-human CD354 (TREM-1) Antibody
- 产品名称：
- Purified anti-human CD354 (TREM-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 316102
- 产品应用：
- 316102
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human TREM-1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
ELISA Capture, WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
ELISA Capture: The purified TREM-37 antibody is useful as a capture antibody for TREM-1 specific sandwich ELISA, when used in conjunction with the biotinylated TREM-26 antibody (Cat. No. 314904) as a detection antibody.
- RRID
- AB_2241002 (BioLegend Cat. No. 316102)
- Structure
- Type I membrane protein, 30 kD, contains immunoglobulin-like V-type domain. Alternatively spliced variant may be secreted.
- Distribution
- Expressed in adult liver, lung, and spleen, lower expression in lymph node, placenta, spinal cord, and heart. Expression on peripheral blood monocytes and granulocytes.
- Function
- Stimulates neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines and the upregulation of surface activation markers. Amplifies inflammatory responses to fungal and bacterial
- Interaction
- DAP12
- Modification
- Glycosylated
- Cell Type
- Monocytes, Granulocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokines/Chemokines
- Antigen References
-
1. Bouchon A, et al. 2001. Nature 410:1103.
2. Bouchon A, et al. 2000. J. Immunol. 164:4991.
3. Gingras MC, et al. 2002. Mol. Immunol. 38:817.
- Regulation
- Upregulated by bacteria, fungi, and LPS
- Gene ID
- 54210 View all products for this Gene ID
- UniProt
- View information about CD354 on UniProt.org
