PE anti-human CD286 (TLR6) Antibody
- 产品名称：
- PE anti-human CD286 (TLR6) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 334707
- 产品应用：
- 334707
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2394 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human TLR6 transfected Ba/F3 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications include: blocks cytokine production induced by MALP-2 and peptidoglycan(1)
- Application References
(PubMed link indicates BioLegend citation) -
- Nakao Y, et al. 2005. J. Immunol. 174:1566
- Product Citations
-
- Whitmore L, et al. 2016. J Immunol. 196: 1376 - 1386. PubMed
- RRID
- AB_2205398 (BioLegend Cat. No. 334707) AB_2205397 (BioLegend Cat. No. 334708)
- Structure
- Type I transmembrane protein characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain, colocalized with TLR2 at the cell surface
- Distribution
- Monocytes/macrophages, dendritic cells, granulocytes
- Function
- Activates innate host defense against diverse set of pathogens
- Ligand/Receptor
- Diacylated lipoprotein, peptidoglycan
- Cell Type
- Monocytes, Macrophages, Dendritic cells, Granulocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Toll Like Receptors
- Antigen References
-
1. Takeuchi O, et al. 2001. Int. Immunol. 13:933
2. Shimizu T, et al. 2005. J. Immunol. 175:4641
3. Into T, et al. 2004. Cell Microbiol. 6:187
- Gene ID
- 10333 View all products for this Gene ID
- UniProt
- View information about CD286 on UniProt.org
