Biotin anti-human CD286 (TLR6) Antibody
- 产品名称：
- Biotin anti-human CD286 (TLR6) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 334705
- 产品应用：
- 334705
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human TLR6 transfected Ba/F3 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications include: blocks cytokine production induced by MALP-2 and peptidoglycan(1)
- Application References
(PubMed link indicates BioLegend citation) -
- Nakao Y, et al. 2005. J. Immunol. 174:1566
- RRID
- AB_1186049 (BioLegend Cat. No. 334705)
- Structure
- Type I transmembrane protein characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain, colocalized with TLR2 at the cell surface
- Distribution
- Monocytes/macrophages, dendritic cells, granulocytes
- Function
- Activates innate host defense against diverse set of pathogens
- Ligand/Receptor
- Diacylated lipoprotein, peptidoglycan
- Cell Type
- Monocytes, Macrophages, Dendritic cells, Granulocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Toll Like Receptors
- Antigen References
-
1. Takeuchi O, et al. 2001. Int. Immunol. 13:933
2. Shimizu T, et al. 2005. J. Immunol. 175:4641
3. Into T, et al. 2004. Cell Microbiol. 6:187
- Gene ID
- 10333 View all products for this Gene ID
- UniProt
- View information about CD286 on UniProt.org
