Purified anti-human CD281 (TLR1) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3612	1

规格

价格

库存

100µg

￥ 3612

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human TLR1 transfected Ba/F3

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IP, ICC - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per 10⁶ cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Other reported applications include immunoprecipitation¹ and immunofluorescence¹.

Application References (PubMed link indicates BioLegend citation)

Nakao Y, et al. 2005. J. Immunol. 174:1566. (BA IP FC IF) PubMed

RRID

AB_1186023 (BioLegend Cat. No. 334502)

Antigen Details

Structure: Type I transmembrane protein characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain, heterodimer with TLR2
Distribution: Monocytes/macrophages, dendritic cells
Function: Coreceptor with TLR2 to activate innate host defense against diverse set of pathogens
Ligand/Receptor: Microbial lipoproteins, peptidoglycans, lipoteichoic acid
Cell Type: Dendritic cells, Macrophages, Monocytes
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules, Toll Like Receptors
Antigen References: 1. Hoebe K, et al. 2005. Nature 433:523.
2. Sandor F, et al. 2003. J. Cell Biol. 162:1099.
3. Takeuchi O, et al. 2002. J. Immunol. 169:10.
4. Wyllie D, et al. 2000. J. Immunol. 165:7125.
5. Buwitt-Beckmann U, et al. 2006. J. Biol. Chem. 281:9049.
Gene ID: 7096 View all products for this Gene ID
UniProt: View information about CD281 on UniProt.org

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