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首页 > 抗体蛋白 > 抗体
APC anti-mouse CD150 (SLAM) Antibody
产品名称：
APC anti-mouse CD150 (SLAM) Antibody
产品类别：
抗体
产品编号：
115909
产品应用：
115909
[价格]
规格 价格 库存
25µg ￥ 1498 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse SLAM-human IgG1 fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD150 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

The TC15-12F12.2 antibody has been reported to enhance the production of IFN-? by Th1 cells stimulated through TCR. Additional reported applications (for the relevant formats) include: immunoprecipitaion17, enhancing IFN-? production by Th1 cells when stimulated with CD31, and inhibiting CD3 induced T cell proliferation6. The Ultra-LEAF? purified antibody (Endotoxin <0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 115949 & 115950).

Application References

(PubMed link indicates BioLegend citation)
  1. Castro AG, et al. 1999. J. Immunol. 163:5860. (FC, Costim, IP)
  2. Forsberg EC, et al. 2005. PLoS Genet. 1:e28. (FC)
  3. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (FC)
  4. Cannons JL, et al. 2006. J. Exp. Med. 203:1551. (FC)
  5. Umemoto T, et al. 2006. J. Immunol. 177:7733. (FC)
  6. Jordan MA, et al. 2007. J. Immunol. 178:1618. (FC, Block) PubMed
  7. Jung Y, et al. 2007. Blood 110:82. PubMed
  8. Pimanda JE, et al. 2007. Proc. Natl. Acad. Sci. USA 104:840.
  9. Sugiyama T, et al. 2007. Proc. Natl. Acad. Sci. USA 104:175.
  10. Kim I, et al. 2006. Blood 108:737. PubMed
  11. Ema H, et al. 2006. Nat Protoc. 1:2979. PubMed
  12. Fraser ST, et al. 2007. Blood 109:4616. PubMed
  13. Jung Y, et al. 2008. Stem Cells. 26:2042. Pubmed
  14. Song J, et al. 2010. Blood 115:2592. PubMed
  15. Cridland SO, et al. 2009. Blood Cell. Mol. Dis. 43:149. (FC) PubMed
  16. Morita Y, et al. 2010. J. Exp Med. 207:1173. PubMed
  17. Talaei N, et al. 2015. J. Immunol. 195(10):4623. PubMed
Product Citations
  1. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  2. Nagamachi A, et al. 2021. J Clin Invest. 131:. PubMed
  3. Foudi A, et al. 2014. J Exp Med. 211:909. PubMed
  4. Krzeptowski W, et al. 2021. Antioxidants (Basel). 10:00. PubMed
  5. Castiello MC, et al. 2020. J Allergy Clin Immunol. . PubMed
  6. Hreha TN, et al. 2020. Front Immunol. 1.597916667. PubMed
  7. Wong J, et al. 2015. Elife. 3: 07839. PubMed
  8. Yamamoto R et al. 2018. Cell stem cell. 22(4):600-607 . PubMed
  9. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  10. Sun Z, et al. 2021. eLife. 10:00. PubMed
  11. Nguyen DTT, et al. 2020. Nat Commun. 11:2026. PubMed
  12. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  13. Kurkewich J, et al. 2016. PLoS One. 11: 0161468. PubMed
  14. Di Genua C, et al. 2020. Cancer Cell. 37(5):690-704.e8.. PubMed
  15. Comazzetto S et al. 2018. Cell stem cell. 24(3):477-486 . PubMed
  16. Dawar S, et al. 2016. Cell Death Dis. 7:e2509. PubMed
  17. Tang D, et al. 2016. J Exp Med. 213: 535-553. PubMed
  18. Zaro BW, et al. 2020. eLife. 9:00. PubMed
  19. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  20. Shen C, et al. 2020. Cell Stem Cell. 27:64. PubMed
  21. Baumgartner C et al. 2018. Cell stem cell. 22(6):879-892 . PubMed
  22. Cheng Y, et al. 2019. Cell Rep. 28:1703. PubMed
  23. Hermetet F, et al. 2019. Nat Commun. 10:523. PubMed
  24. Sevin M, et al. 2018. Nat Commun. 9:1431. PubMed
  25. Cerisoli F, et al. 2009. Haematologica. 94:318. PubMed
  26. Sinclair A, et al. 2016. Blood. 128: 371 - 383. PubMed
  27. Takiguchi M, et al. 2013. PLoS One. 8:e54009. PubMed
  28. DeGregori C 2008. Blood. 112:4466. PubMed
  29. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  30. Di Genua C, et al. 2019. Haematologica. 104:2215. PubMed
  31. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  32. Xie X, et al. 2015. Sci Rep. 5: 18115. PubMed
  33. Tung LT, et al. 2021. Cell Death Dis. 12:923. PubMed
  34. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  35. Ortega-Molina A, et al. 2021. Cell Reports. 36(2):109372. PubMed
  36. Magee JA, et al. 2021. Stem Cell Reports. 16:20. PubMed
  37. Lee SG, et al. 2020. J Nucl Med. . PubMed
  38. Merchant A, et al. 2011. Blood. 118:6572. PubMed
  39. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  40. S?wen P et al. 2018. eLife. 7 pii: e41258. PubMed
  41. Nakagawa MM, et al. 2018. Cell Rep. 25:2094. PubMed
  42. Li X, et al. 2019. Stem Cells. 37:937. PubMed
  43. Fielding C, et al. 2022. Nat Commun. 13:543. PubMed
  44. Siu K, et al. 2014. Mol Cell Biol. 34:3244. PubMed
  45. Rowe R, et al. 2016. J Exp Med. 213: 1497 - 1512. PubMed
  46. Kang YA, et al. 2020. J Exp Med. 217:00:00. PubMed
  47. Li ZG, et al. 2020. Chin Med J (Engl). 1943:133. PubMed
  48. Park SM et al. 2018. Cell stem cell. 24(1):153-165 . PubMed
  49. Pimanda J, et al. 2008. Blood. 112:4512. PubMed
  50. Huang WC, et al. 2019. Int J Hyperthermia. 36:1255. PubMed
  51. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  52. Jee D et al. 2018. Molecular cell. 69(2):265-278 . PubMed
  53. Hacein-Bey-Abina S, et al. 2020. Exp Hematol. 88:15. PubMed
RRID
AB_493461 (BioLegend Cat. No. 115909) AB_493460 (BioLegend Cat. No. 115910)

Antigen Details

Structure
Ig superfamily, 75-95 kD
Distribution

Thymocytes, T cell subset, B lymphocytes, dendritic cells, endothelial cells

Function
B cell and dendritic cell costimulation
Ligand/Receptor
CD150
Cell Type
B cells, Dendritic cells, Endothelial cells, T cells, Thymocytes, Tregs
Biology Area
Costimulatory Molecules, Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Cocks BG, et al. 1995. Nature 376:260.
2. Punnonen J, et al. 1997. J. Exp. Med. 185:993.
3. Sidorenko SP, et al. 1993. J. Immunol. 151:4614.

Gene ID
27218 View all products for this Gene ID
UniProt
View information about CD150 on UniProt.org

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