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首页 > 抗体蛋白 > 抗体
Purified anti-TRAF6 Antibody
产品名称：
Purified anti-TRAF6 Antibody
产品类别：
抗体
产品编号：
654501
产品应用：
654501
[价格]
规格 价格 库存
25µg ￥ 2226 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial recombinant human TRAF6 protein (352-522 aa) expressed from E. coli.
Formulation
This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.05% sodium azide.
Preparation
Affinity purified
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, store undiluted between 2°C and 8°C.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Tan Y, et al. 2019. Cell. 177:384. PubMed
  2. Ben J, et al. 2019. Nat Commun. 10:1801. PubMed
  3. Mitsumura T, et al. 2018. Blood Adv. 2.502083333. PubMed
RRID
AB_2561867 (BioLegend Cat. No. 654501) AB_2561868 (BioLegend Cat. No. 654502)

Antigen Details

Structure
522 amino acids, predicted MW of 60 kD
Distribution
Cytoplasm, Nucleus
Function
A unique member of the TRAF family of adaptor proteins involved in both the TNF receptor superfamily and the interleukin-1 receptor (IL-1R)/Toll-like receptor (TLR) superfamily signal transduction pathways
Interaction
Homotrimer, homooligomer; Binds to TNFRSF5/CD40 and TNFRSF11A/RANK; Interacts with RBCK1 and TRAF3IP2
Biology Area
Cell Biology, Neuroinflammation, Neuroscience, Signal Transduction, Ubiquitin/Protein Degradation
Antigen References

1. Rothe M, et al. 1994. Cell 78:681.
2. Arch RH, et al. 1998. Genes Dev. 12:2821.
3. Ye H, et al. 2002. Nature 418:443.
4. Yang WL, et al. 2009. Science 325:1134.
5. Qu F, et al. 2012. Mol. Cell. Biol. 32:3925.
6. Akiyama T, et al. 2012. Front Immunol. 3:278.
7. Wei J, et al. 2012. PLoS One 1:e49567.

Gene ID
7189 View all products for this Gene ID 22034 View all products for this Gene ID
UniProt
View information about TRAF6 on UniProt.org

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