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Purified anti-α-Synuclein Antibody (Previous
产品名称:
Purified anti-α-Synuclein Antibody (Previous
产品类别:
抗体
产品编号:
824301
产品应用:
824301
[价格]
规格 价格 库存
100µL ¥ 3850 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody is effective in formalin-fixed paraffin-embedded immunohistochemical staining (IHC-P).

Application References

(PubMed link indicates BioLegend citation)
  1. Beach, Thomas G, et. al. Evaluation of ?-synuclein immunohistochemical methods used by invited experts. Acta Neuropathol, 116(3): 277-288, September 2008.
  2. Uryu K, et al. 2003. Exp. Neurol. 184:214. (WB, IHC)
  3. Neumann M, et al. 2002. J. Clin. Invest. 110:1429. (IHC)
  4. Tsika E, et al. 2010. J. Neurosci. 30:3409. (WB)
  5. Fan Y, et al. 2006. Hum. Mol. Genet. 15:3002. (IHC)
  6. Tran HT, et al. 2014. Cell Rep. 7:2054. (IF, functional)
  7. Giasson BI, et al. 2002. Neuron 34:521. (EM)
  8. Luk KC, et al. 2009. Proc. Natl. Acad. Sci. USA 106:20051. (IF)
  9. Soper JH, et al. 2008. Mol. Biol. Cell. 19:1093. (IF, WB)
  10. Wilson CA, et al. 2004. J. Cell. Biol. 165:335. (IF, WB)
  11. Colla E, et al. 2012. J. Neurosci. 32:3301. (WB)
Product Citations
  1. Pantazopoulou M, et al. 2020. J Neurochem. 156:880. PubMed
  2. Mazzulli J, et al. 2016. J Neurosci. 36: 7693 - 7706. PubMed
  3. Cuddy LK, et al. 2020. Neuron. 104(5):869-884.e11.. PubMed
  4. Tao Y, et al. 2022. Nat Commun. 13:4226. PubMed
  5. Covell DJ, et al. 2017. Neuropathol Appl Neurobiol. 43:604. PubMed
  6. Zunke F et al. 2017. Neuron. 97(1):92-107 . PubMed
  7. Sargent D et al. 2017. Journal of neurochemistry. 143(1):126-135 . PubMed
  8. Stojkovska I, et al. 2021. STAR Protocols. 2(1):100372. PubMed
  9. Nicot S, et al. 2019. FASEB J. 33:12073. PubMed
  10. Kahriman A, et al. 2021. Acta Neuropathologica Communications. 9(1):118. PubMed
RRID
AB_2564879 (BioLegend Cat. No. 824301)

Antigen Details

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
α-Synuclein
Gene ID
6622 View all products for this Gene ID
UniProt
View information about alpha-Synuclein on UniProt.org

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