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Anti-Synuclein-α/β, 130-140 Antibody (P
产品名称:
Anti-Synuclein-α/β, 130-140 Antibody (P
产品类别:
抗体
产品编号:
836602
产品应用:
836602
[价格]
规格 价格 库存
25µL ¥ 2058 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Syn 202 was raised using recombinant alpha and beta synucleins and recognizes residues 130-140 in alpha and beta synuclein.
Preparation
Ascites
Concentration
The concentration is not quantified as this product is sold as undiluted crude mouse ascites fluid. The concentration might vary from lot-to-lot and an estimated concentration would be 1-3 mg/ml.
Storage & Handling
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C.
Application

IHC-P -?Quality tested
WB -?Verified
EM, ICC, IP -?Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a dilution range of 1:500-1:1000 is suggested. For Western blotting, the suggested dilution of this reagent is 1:500-1:1000. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody is effective in immunoblotting (WB), immunoprecipitation (IP), and immunohistochemistry of formalin-fixed paraffin-embedded tissue sections (IHC-P).

Application References

(PubMed link indicates BioLegend citation)
  1. Nibe K,?et al. 2009.?Vet. Pathol.?46(3):474-83.?(IHC)
  2. Giasson BI,?et al. 2000.?J. Neurosci. Res.?59(4):528-33.
  3. Mazzulli JR, et. al. 2011. Cell 146:37. (WB)
  4. Giasson BI, et. al. 1999. J. Biol. Chem. 274:7619. (EM)
  5. Giasson BI, et. al. 2002. Neuron. 34:521. (ICC)
  6. Usenovic M, et. al. 2012. J. Neurosci. 32:4240. (WB) PubMed
  7. Morrison GJ, et. al. 2012. PLoS One 7:e43288. (IP)
  8. Knight AL, et. al. 2014. Cell Metab. 20:145. (WB) PubMed
Product Citations
  1. Knight A, et al. 2014. Cell Metab. 20:145-157. PubMed
  2. Usenovic M, et al. 2012. J Neurosci. 32:4240-4246. PubMed
  3. Stoyka LE, et al. 2021. eneuro. 8(3):. PubMed
RRID
AB_2734606 (BioLegend Cat. No. 836602) AB_2565365 (BioLegend Cat. No. 836601)

Antigen Details

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
α-Synuclein
Gene ID
6622 View all products for this Gene ID
UniProt
View information about Synuclein-alpha/beta, 130-140 on UniProt.org

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