Purified anti-human CD106 Antibody
- 产品名称：
- Purified anti-human CD106 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 305802
- 产品应用：
- 305802
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-P - Verified
ICC, IP, ELISA - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume.?For immunohistochemical staining on formalin-fixed paraffin-embedded tissue sections, the suggested use of this reagent is 5.0?- 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunofluorescence3, immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation2,?ELISA2 capture for sCD106, and spatial biology (IBEX)5,6.
- Application References
(PubMed link indicates BioLegend citation) -
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
- Leca G, et al. 1995. J. Immunol. 154:1069. (ELISA IP)
- Yen YT, et al. 2006. J. Virol. 80:2648. (IF) PubMed
- Dmitrieva NI, et al. 2015. PloS One.10:128870. PubMed
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Pilbauerova N, et al. 2021. Int J Mol Sci. 22:. PubMed
- Dmitrieva N, Burg M 2015. PLoS One. 10:128870. PubMed
- Propson NE, et al. 2020. J Clin Invest. . PubMed
- Piao W, et al. 2020. Cell Reports. 30(4):1052-1062.e5.. PubMed
- Yen Y, et al. 2006. J Virol. 80:2684. PubMed
- Eriksson E, et al. 2017. Clin Cancer Res. 5.018055556. PubMed
- Gunasekaran M, et al. 2018. J Immunol. 200:2535. PubMed
- RRID
- AB_314558 (BioLegend Cat. No. 305802)
- Structure
- Ig superfamily, type I glycoprotein, 110 kD
- Distribution
-
Activated endothelial cells, endothelial progenitors, follicular dendritic cells
- Function
- Leukocyte adhesion, transmigration, costimulation
- Ligand/Receptor
- VLA-4 (CD49d/CD29)
- Cell Type
- Dendritic cells, Endothelial cells, Mesenchymal Stem Cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Neuroinflammation, Neuroscience, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Carlos T, et al. 1994. Blood 84:2068.
2. Jones E, et al. 1995. Nature 373:539.
- Gene ID
- 7412 View all products for this Gene ID
- UniProt
- View information about CD106 on UniProt.org
