Purified anti-RIG-1 Antibody
- 产品名称：
- Purified anti-RIG-1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 635201
- 产品应用：
- 635201
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Peptide-KLH, C-terminal end of murine RIG-1
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store?undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Wang W, et al. 2016. Proc Natl Acad Sci U S A. 113: 9581 - 9586. PubMed
- RRID
- AB_940599 (BioLegend Cat. No. 635201)
- Structure
- RIG-1 is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kD.
- Distribution
-
Cytoplasm.
- Function
- Involved in innate immune defense against viruses. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 is one of the key intracellular receptors that sense intracellular viral infection and trigger a signal for
- Interaction
- Cardif
- Biology Area
- Cell Biology, Transcription Factors
- Antigen References
-
1. Imaizumi T, et al. 2002. Biochem. Biophys. Res. Commun. 292:274
2. Kato H, et al. 2006. Nature 441:101
3. Kato H, et al. 2005. Immunity 23:19
- Gene ID
- 109906 View all products for this Gene ID
- UniProt
- View information about RIG-1 on UniProt.org
