Purified anti-human CD213a1 (IL-13Rα1) Antib
- 产品名称:
- Purified anti-human CD213a1 (IL-13Rα1) Antib
- 产品类别:
- 抗体
- 产品编号:
- 360402
- 产品应用:
- 360402
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant extracellular domain of human IL-13 receptor α1 chain
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2562552 (BioLegend Cat. No. 360402)
- Structure
- Single-pass type I membrane protein 48.7 kD; forms a heterodimer with IL-4R
- Distribution
-
Expressed at low levels on myeloid cells; also expressed on activated T and B cells, Th17 cells
- Function
- Functional receptor for IL-13
- Interaction
- Interacts with TYK2 and can lead to downstream activation of JAK1, STAT3, and STAT6
- Ligand/Receptor
- IL-13
- Cell Type
- B cells, T cells, Th17
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Aman MJ, et al. 1996. J. Biol. Chem. 271:29265.
2. Osawa M, et al. 2000. Immunogenetics. 51:974.
3. Arima K, et al. 2005. J. Biol. Chem. 280:24915.
4. LaPorte SL, et al. 2008. Cell. 132:259.
5. Newcomb DC, et al. 2011. J. Allerg. Clin. Immunol. 127:1006.
- Gene ID
- 3597 View all products for this Gene ID
- UniProt
- View information about CD213a1 on UniProt.org