Purified anti-Spastin Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1484	1

规格

价格

库存

25µg

￥ 1484

Product Details

Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human spastin protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2814618 (BioLegend Cat. No. 868201) AB_2814619 (BioLegend Cat. No. 868202)

Antigen Details

Structure

Human spastin is a 616 amino acid protein with a predicted molecular mass of 67 kD.

Distribution

Tissue distribution: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. The short isoform may predominate in the brain and spinal cord.
Cellular distribution: Cytoskeleton, endoplasmic reticulum, nucleus, and membrane.

Function

Spastin is involved in the regulation of microtubule severing.

Interaction

Spastin mostly forms homohexamer.

Cell Type

Neurons

Biology Area

Cell Biology, Cell Motility/Cytoskeleton/Structure, Neurodegeneration, Neuroscience

Molecular Family

Cytoskeletal Proteins

Antigen References

Hazan J. et al. 1999. Nat Genet. 23(3):296-303.
Solowska?JM. et al. 2014. J Neurosci.?34(5):1856-67.?

Gene ID

6683 View all products for this Gene ID

UniProt

View information about Spastin on UniProt.org

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