FITC anti-CD105 (Endoglin) Antibody
- 产品名称：
- FITC anti-CD105 (Endoglin) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 800505
- 产品应用：
- 800505
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1316 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CD105 (Endoglin) isolated from acute lymphoblastic leukemia cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- C Li, R Grady, BK Seon, SE Duff, S Abdalla, A Renehan, ST O'Dwyer, N Haboubi, S Kumar. Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 antibody in colorectal cancer patients correlate with poor prognosis. Br J Cancer 88:1424-1431, 2003.
- Sanz-Rodriguez, Francisco, et al. Endoglin regulates cytoskeletal organization through binding to ZRP-1 a member of the Lim family of proteins. J Biol Chem 279(31):32858-68, 2004.
- Takahashi N, et al. Association of Serum Endoglin with Metastasis in Patients with Colorectal, Breast, and Other Solid Tumors, and SuppressiveEffect of Chemotherapy on the Serum Endoglin. Clin. Cancer Res.: 7(3): 524-532, Mar 2001.
- Seon BK, Matsuno F, Haruta Y, Kondo M, and Barcos M. Long-lasting complete inhibition of human solid tumors in SCID mice by targeting endothelial cells of tumor vasculature with antihuman endoglin immunotoxin. Clin. Cancer Res.: 3(7): 1031-1044, Jul 1997.
- Haruta Y, Seon BK. Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6. PNAS: 83: 7898-7902, Oct 1986.
- Product Citations
-
- Tu S, et al. 2020. Cellular Signalling. 73:109695. PubMed
- Xu H, et al. 2022. Cell Death Dis. 13:478. PubMed
- RRID
- AB_2687058 (BioLegend Cat. No. 800505) AB_2687059 (BioLegend Cat. No. 800506)
