Purified anti-GFAP (Cocktail) -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1568	1

规格

价格

库存

25µg

￥ 1568

Product Details

Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: IHC-P - Quality tested
ICC, WB - Verified
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10.0 ?g/ml is suggested.?For immunocytochemistry, a concentration range of 1.0 - 10.0 μg/ml is recommended. For Western blotting, the suggested use of this reagent is 0.1 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Antibody is less reactive in mouse tissue in IHC-P.

Multiple protein fragments ranging from 38 to 48 kD have been reported in human CNS lysates resulting from caspase- and calpain-mediated cleavage of GFAP.
RRID: AB_2728558 (BioLegend Cat. No. 837603) AB_2728559 (BioLegend Cat. No. 837604)

Antigen Details

Structure

GFAP is a 432 amino acid protein with a molecular mass of ~50 kD.

Distribution

Tissue distribution: GFAP is expressed by numerous cell types of the central nervous system (CNS) including astrocytes, ependymal cells, and Bergmann glia cells (protoplasmic astrocyte). GFAP is expressed in cells lacking fibronectin.
Cellular distribution: Cytoskeleton and cytosol

Function

GFAP is a class-III intermediate filament and a structural constituent of the cytoskeleton. It is a cell-specific marker that is used to distinguish astrocytes from other glial cells during the development of the CNS.

Cell Type

Astrocytes

Biology Area

Cell Biology, Neuroscience, Neuroscience Cell Markers

Molecular Family

Intermediate Filaments

Antigen References