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Purified anti-GFAP Antibody
产品名称:
Purified anti-GFAP Antibody
产品类别:
抗体
产品编号:
837504
产品应用:
837504
[价格]
规格 价格 库存
100µg ¥ 3864 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested
WB - Verified

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10 μg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Zelic M, et al. 2021. Cell Reports. 35(6):109112. PubMed
  2. Hagan N, et al. 2020. Cell Death Dis. 1.086111111. PubMed
RRID
AB_2632641 (BioLegend Cat. No. 837504)

Antigen Details

Structure
GFAP is a 432 amino acid protein with a molecular mass of approximately 50 kD.
Distribution

Tissue distribution: GFAP is expressed by numerous cell types of the central nervous system (CNS) including astrocytes, ependymal cells, and Bergmann glia cells (protoplasmic astrocyte). GFAP is expressed in cells lacking fibronectin.

Cellular distribution: cytoskeleton and cytosol

Function
GFAP is a class-III intermediate filament and a structural constituent of the cytoskeleton. It is a cell-specific marker that is used to distinguish astrocytes from other glial cells during the development of the CNS.
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
Molecular Family
Intermediate Filaments
Antigen References

1. Khakh BS, Sofroniew MV. 2015. Nat. Neurosci. 18:942-52. PubMed

Gene ID
2670 View all products for this Gene ID
UniProt
View information about GFAP on UniProt.org

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