Anti-GFAP Antibody (Previously Covance catalog# SM
- 产品名称:
- Anti-GFAP Antibody (Previously Covance catalog# SM
- 产品类别:
- 抗体
- 产品编号:
- 837501
- 产品应用:
- 837501
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Preparation
- Ascites
- Concentration
- The concentration is not quantified as this product is sold as undiluted crude mouse ascites fluid. The concentration might vary from lot-to-lot and an estimated concentration would be 1-3 mg/ml.
- Storage & Handling
- Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
- Application
-
IHC-P - Quality tested
WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a dilution range of 1/1000 - 1/2000 is suggested. For Western blotting, the suggested use of this reagent is 1/2000 - 1/4000. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2565377 (BioLegend Cat. No. 837501) AB_2565378 (BioLegend Cat. No. 837502)
- Structure
- GFAP is a 432 amino acid protein with a molecular mass of approximately 50 kD.
- Distribution
-
Tissue distribution: GFAP is expressed by numerous cell types of the central nervous system (CNS) including astrocytes, ependymal cells, and Bergmann glia cells (protoplasmic astrocyte). GFAP is expressed in cells lacking fibronectin.
Cellular distribution: cytoskeleton and cytosol
- Function
- GFAP is a class-III intermediate filament and a structural constituent of the cytoskeleton. It is a cell-specific marker that is used to distinguish astrocytes from other glial cells during the development of the CNS.
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Intermediate Filaments
- Gene ID
- 2670 View all products for this Gene ID
- UniProt
- View information about GFAP on UniProt.org