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Purified anti‐GFAP (Cocktail)
产品名称:
Purified anti‐GFAP (Cocktail)
产品类别:
抗体
产品编号:
835303
产品应用:
835303
[价格]
规格 价格 库存
25µg ¥ 1568 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested
ICC, WB - Verified

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 ?g/ml is suggested.?For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended.?For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Multiple protein fragments ranging from 38 to 48 kD have been reported in human CNS lysates resulting from caspase- and calpain-mediated cleavage of GFAP.

RRID
AB_2728544 (BioLegend Cat. No. 835303) AB_2728545 (BioLegend Cat. No. 835304)

Antigen Details

Structure
GFAP is a 432 amino acid protein with a molecular mass of ~50 kD.
Distribution

Tissue distribution: GFAP is expressed by numerous cell types of the central nervous system (CNS) including astrocytes, ependymal cells, and Bergmann glia cells (protoplasmic astrocyte). GFAP is expressed in cells lacking fibronectin.
Cellular distribution: Cytoskeleton and cytosol

Function
GFAP is a class-III intermediate filament and a structural constituent of the cytoskeleton. It is a cell-specific marker that is used to distinguish astrocytes from other glial cells during the development of the CNS.
Cell Type
Astrocytes
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers
Molecular Family
Intermediate Filaments
Gene ID
2670 View all products for this Gene ID
UniProt
View information about GFAP on UniProt.org

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