PerCP/Cyanine5.5 anti-human CD3 Antibody
- 产品名称:
- PerCP/Cyanine5.5 anti-human CD3 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 344807
- 产品应用:
- 344807
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
¥ 2394 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Kan EA, et al. 1983. J. Immunol. 131:536.
- Wood GS, et al. 1985. Am. J. Pathol. 120:371.
- Van Dongen JJM, et al. 1988. Blood 71:603. (WB)
- Haringman JJ, et al. 2005. Arthritis Res. Ther. 7:R862. (IHC)
- Carbone A, et al. 1999. Blood 93:2319. (IHC)
- Goval JJ, et al. 2006. J. Histochem. Cytochem. 54:75. (IF)
- Rutjens E, et al. 2007. J. Immunol. 178:1702.
- Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Kuri-Maga?a H, et al. 2018. Front Immunol. 9:2679. PubMed
- Chabi S, et al. 2020. Cell Reports. 29(8):2307-2320.e6.. PubMed
- Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed
- Yu N, et al. 2018. Genes Immun. 10.1038/s41435-017-0007-7. PubMed
- Cho JW, et al. 2021. Nat Commun. 12:6068. PubMed
- Antonucci L, et al. 2020. Journal of Immunology Research. 3257.929861. PubMed
- Orrantia A, et al. 2022. iScience. 25:105235. PubMed
- Giesecke C, et al. 2017. Cytometry A. 10.1002/cyto.a.23250. PubMed
- , et al. 2021. Eur J Immunol. 51:2708. PubMed
- Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
- McDonnell A, et al. 2017. BMC Cancer . 10.1186/s12885-017-3403-5. PubMed
- Kim ST, et al. 2021. J Immunother Cancer. 9:. PubMed
- Inglis H, et al. 2015. J Vis Exp. 97: 52484. PubMed
- RRID
- AB_10641704 (BioLegend Cat. No. 344807) AB_10640736 (BioLegend Cat. No. 344808)
- Structure
- Ig superfamily, with the subunits of CD3γ, CD3δ, CD3ζ, (CD247) and TCR (α/β or γ/δ) forms CD3/TCR complex, 20 kD
- Distribution
-
Mature T and NK T cells, during thymocyte differentiation
- Function
- Antigen recognition, signal transduction, T cell activation
- Ligand/Receptor
- Peptide antigen bound to MHC
- Cell Type
- NKT cells, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, TCRs
- Antigen References
-
1. Barclay N, et al. 1993. The Leucocyte FactsBook. Academic Press. San Diego.
2. Beverly P, et al. 1981. Eur. J. Immunol. 11:329.
3. Lanier L, et al. 1986. J. Immunol. 137:2501.
- Gene ID
- 916 View all products for this Gene ID
- UniProt
- View information about CD3 on UniProt.org