PerCP anti-human CD3 Antibody
- 产品名称：
- PerCP anti-human CD3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 344813
- 产品应用：
- 344813
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2002 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PerCP under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.
- Application References
(PubMed link indicates BioLegend citation) -
- Kan EA, et al. 1983. J. Immunol. 131:536.
- Wood GS, et al. 1985. Am. J. Pathol. 120:371.
- Van Dongen JJM, et al. 1988. Blood 71:603. (WB)
- Haringman JJ, et al. 2005. Arthritis Res. Ther. 7:R862. (IHC)
- Carbone A, et al. 1999. Blood 93:2319. (IHC)
- Goval JJ, et al. 2006. J. Histochem. Cytochem. 54:75. (IF)
- Rutjens E, et al. 2007. J. Immunol. 178:1702.
- Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Fowler DW, et al. 2017. Cancer Immunol Immunother. 66:1205. PubMed
- Arra A, et al. 2021. Oncoimmunology. 10:1938475. PubMed
- Dockree T, et al. 2016. Immunol Cell Biol. 95:68-76. PubMed
- Wu K, et al. 2021. Aging (Albany NY). 13:. PubMed
- Reif T, et al. 2021. Cell Reports Medicine. 2(6):100317. PubMed
- Eriksson E, et al. 2016. Gene Ther. 10.1038/gt.2016.80. PubMed
- Giesecke C, et al. 2017. Cytometry A. 10.1002/cyto.a.23250. PubMed
- Corrah T, et al. 2011. J Virol. 85:3367. PubMed
- Srinivasan A, et al. 2014. Biol Blood Marrow Transplant. 20:1224. PubMed
- Borhis G, et al. 2013. J Immunol. 190:2924. PubMed
- Tarke A, et al. 2022. Cell. 185:847. PubMed
- Cuesta M, et al. 2016. J Immunol. 196: 2466 - 2475. PubMed
- Eccles JD, et al. 2020. Cell Rep. 30:351. PubMed
- Gooneratne S, et al. 2015. J Virol. 89:97. PubMed
- Madhavi V, et al. 2015. J Infect Dis. 211:529. PubMed
- Mozhgani SH, et al. 2019. Retrovirology. 16:46. PubMed
- Turaj AH et al. 2017. Cancer cell. 32(6):777-791 . PubMed
- Kaewchim K, et al. 2021. Molecules. 26:. PubMed
- Cohen Z, et al. 2020. Biomed Rep. 13:17. PubMed
- Keck S, et al. 2021. Cellular and Molecular Gastroenterology and Hepatology. 12(2):507-545. PubMed
- Misheva M, et al. 2022. Nat Commun. 13:139. PubMed
- Kang HM, et al. 2018. Nat Biotechnol. 36:89. PubMed
- RRID
- AB_10641841 (BioLegend Cat. No. 344813) AB_10639948 (BioLegend Cat. No. 344814)
- Structure
- Ig superfamily, with the subunits of CD3γ, CD3δ, CD3ζ, (CD247) and TCR (α/β or γ/δ) forms CD3/TCR complex, 20 kD
- Distribution
-
Mature T and NK T cells, during thymocyte differentiation
- Function
- Antigen recognition, signal transduction, T cell activation
- Ligand/Receptor
- Peptide antigen bound to MHC
- Cell Type
- NKT cells, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, TCRs
- Antigen References
-
1. Barclay N, et al. 1993. The Leucocyte FactsBook. Academic Press. San Diego.
2. Beverly P, et al. 1981. Eur. J. Immunol. 11:329.
3. Lanier L, et al. 1986. J. Immunol. 137:2501.
- Gene ID
- 916 View all products for this Gene ID
- UniProt
- View information about CD3 on UniProt.org
