PE/Cyanine7 anti-human CD3 Antibody
- 产品名称：
- PE/Cyanine7 anti-human CD3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 344815
- 产品应用：
- 344815
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2002 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Kan EA, et al. 1983. J. Immunol. 131:536.
- Wood GS, et al. 1985. Am. J. Pathol. 120:371.
- Van Dongen JJM, et al. 1988. Blood 71:603. (WB)
- Haringman JJ, et al. 2005. Arthritis Res. Ther. 7:R862. (IHC)
- Carbone A, et al. 1999. Blood 93:2319. (IHC)
- Goval JJ, et al. 2006. J. Histochem. Cytochem. 54:75. (IF)
- Rutjens E, et al. 2007. J. Immunol. 178:1702.
- Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Alfonso-Dunn R, et al. 2022. Front Immunol. 13:926318. PubMed
- Liu R, et al. 2022. Aging Dis. 13:1576. PubMed
- Nakano M, et al. 2021. Front Immunol. 12:713225. PubMed
- Stras SF, et al. 2020. Developmental Cell. 51(3):357-373.e5.. PubMed
- Frame JM, et al. 2020. Developmental Cell. 55(2):133-149.e6. PubMed
- Nathan A, et al. 2021. Cell. 184(17):4401-4413.e10. PubMed
- Dyring-Andersen B, et al. 2020. Nat Commun. 4.338194444. PubMed
- Moraru M, et al. 2015. J Immunol. 195: 1676-1684. PubMed
- Balle C, et al. 2022. J Clin Invest. :. PubMed
- Sweeney EE, et al. 2020. Nano Res. 13:736. PubMed
- Pascual–García M, et al. 2019. Nat Commun. 10:2416. PubMed
- Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
- Meckiff BJ, et al. 2020. Cell. 183(5):1340-1353.e16. PubMed
- Antonarakis ES, et al. 2018. Clin Cancer Res. 24:4662. PubMed
- Muller YD, et al. 2021. Front Immunol. 12:639818. PubMed
- Bj?rkander S, et al. 2016. Sci Rep. 6:22083. PubMed
- Naranbhai V, et al. 2022. Cell. . PubMed
- Walle T, et al. 2022. Sci Adv. 8:eabh4050. PubMed
- RRID
- AB_10641705 (BioLegend Cat. No. 344815) AB_10640737 (BioLegend Cat. No. 344816)
- Structure
- Ig superfamily, with the subunits of CD3γ, CD3δ, CD3ζ, (CD247) and TCR (α/β or γ/δ) forms CD3/TCR complex, 20 kD
- Distribution
-
Mature T and NK T cells, during thymocyte differentiation
- Function
- Antigen recognition, signal transduction, T cell activation
- Ligand/Receptor
- Peptide antigen bound to MHC
- Cell Type
- NKT cells, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, TCRs
- Antigen References
-
1. Barclay N, et al. 1993. The Leucocyte FactsBook. Academic Press. San Diego.
2. Beverly P, et al. 1981. Eur. J. Immunol. 11:329.
3. Lanier L, et al. 1986. J. Immunol. 137:2501.
- Gene ID
- 916 View all products for this Gene ID
- UniProt
- View information about CD3 on UniProt.org
