GMP PE anti-human CD3 Antibody
- 产品名称：
- GMP PE anti-human CD3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 260098
- 产品应用：
- 260098
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 4326 |
1 |
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, 0.2% (w/v) BSA (origin USA) and a stabilizer.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 25 ?g/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.
- Application References
(PubMed link indicates BioLegend citation) -
- Kan EA,?et al.?1983.?J. Immunol.?131:536.
- Wood GS,?et al.?1985.?Am. J. Pathol.?120:371.
- Van Dongen JJM,?et al.?1988.?Blood?71:603. (WB)
- Haringman JJ,?et al.?2005.?Arthritis Res. Ther.?7:R862. (IHC)
- Carbone A,?et al.?1999.?Blood?93:2319. (IHC)
- Goval JJ,?et al.?2006.?J. Histochem. Cytochem.?54:75. (IF)
- Rutjens E,?et al.?2007.?J. Immunol.?178:1702.
- Kap Y,?et al.?2009.?J. Histochem. Cytochem.?57:1159. (IHC)
- Yoshino N,?et al.?2000.?Exp. Anim. (Tokyo)?49:97. (FC)
- RRID
- AB_2922511 (BioLegend Cat. No. 260098)
- Disclaimer
GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include:
- Batch-to-batch consistency
- Material traceability
- Documented procedures
- Documented employee training
- Equipment maintenance and monitoring records
- Lot-specific certificates of analysis
- Quality audits per ISO 13485:2016
- QA review of released products
- Structure
- Ig superfamily, with the subunits of CD3γ, CD3δ, CD3ζ, (CD247) and TCR (α/β or γ/δ) forms CD3/TCR complex, 20 kD
- Distribution
-
Mature T and NK T cells, during thymocyte differentiation
- Function
- Antigen recognition, signal transduction, T cell activation
- Ligand/Receptor
- Peptide antigen bound to MHC
- Cell Type
- NKT cells, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, TCRs
- Antigen References
-
- Barclay N,?et al.?1993. The Leucocyte FactsBook. Academic Press. San Diego.
- Beverly P,?et al.?1981.?Eur. J. Immunol.?11:329.
- Lanier L,?et al.?1986.?J. Immunol.?137:2501.
- Gene ID
- 916 View all products for this Gene ID
- UniProt
- View information about CD3 on UniProt.org
