FITC anti-human CD3 Antibody
- 产品名称：
- FITC anti-human CD3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 344803
- 产品应用：
- 344803
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1008 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections4,5,8, immunofluorescent staining6, and Western blotting3.
- Application References
(PubMed link indicates BioLegend citation) -
- Kan EA, et al. 1983. J. Immunol. 131:536.
- Wood GS, et al. 1985. Am. J. Pathol. 120:371.
- Van Dongen JJM, et al. 1988. Blood 71:603. (WB)
- Haringman JJ, et al. 2005. Arthritis Res. Ther. 7:R862. (IHC)
- Carbone A, et al. 1999. Blood 93:2319. (IHC)
- Goval JJ, et al. 2006. J. Histochem. Cytochem. 54:75. (IF)
- Rutjens E, et al. 2007. J. Immunol. 178:1702.
- Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Product Citations
-
- Penkava F, et al. 2020. Nat Commun. 3.76875. PubMed
- Chan S, et al. 2022. Nat Cancer. . PubMed
- Chan JA, et al. 2022. Nat Commun. 13:4159. PubMed
- Montes de Oca M, et al. 2016. Cell Rep. 17:399-412. PubMed
- Cao M, et al. 2020. Aging Dis. 1.479861111. PubMed
- Hagan T, et al. 2020. Cell. 178(6):1313-1328.e13.. PubMed
- Bj?rklund &, et al. 2016. Nat Immunol. 17:451-460. PubMed
- Weaver JD, et al. 2022. Oncoimmunology. 11:2141007. PubMed
- Thiel BA, et al. 2021. PLoS One. 16:e0249477. PubMed
- Lu J, et al. 2021. Front Immunol. 12:732612. PubMed
- Lima J, et al. 2016. Reprod Sci. 10.1177/1933719116653680. PubMed
- Mudd PA, et al. 2022. Cell. 185:603. PubMed
- Chheda ZS, et al. 2018. J Exp Med. 9:19490. PubMed
- Prota G, et al. 2020. Cancer Immunol Res. 8:685. PubMed
- Roudko V, et al. 2020. Cell. 183(6):1634-1649.e17. PubMed
- Nagree MS, et al. 2022. EMBO Mol Med. 14:e14297. PubMed
- Carter JA, et al. 2020. Cell Systems. 9(5):475-482.e4.. PubMed
- Cimen Bozkus C, et al. 2021. STAR Protoc. 2:100758. PubMed
- Qing G, et al. 2021. Front Cell Dev Biol. 9:761300. PubMed
- RRID
- AB_2043992 (BioLegend Cat. No. 344803) AB_2043993 (BioLegend Cat. No. 344804)
- Structure
- Ig superfamily, with the subunits of CD3γ, CD3δ, CD3ζ, (CD247) and TCR (α/β or γ/δ) forms CD3/TCR complex, 20 kD
- Distribution
-
Mature T and NK T cells, during thymocyte differentiation
- Function
- Antigen recognition, signal transduction, T cell activation
- Ligand/Receptor
- Peptide antigen bound to MHC
- Cell Type
- NKT cells, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, TCRs
- Antigen References
-
1. Barclay N, et al. 1993. The Leucocyte FactsBook. Academic Press. San Diego.
2. Beverly P, et al. 1981. Eur. J. Immunol. 11:329.
3. Lanier L, et al. 1986. J. Immunol. 137:2501.
- Gene ID
- 916 View all products for this Gene ID
- UniProt
- View information about CD3 on UniProt.org
